Evidence map›Paper›PMID 27153568›Full record

ArticleBioinformatics (Oxford, England)2016

Integrated genome browser: visual analytics platform for genomics.

Nowlan H Freese, David C Norris, Ann E Loraine

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 238 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
238citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

238 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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178 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nowlan H FreeseDepartment of Bioinformatics and Genomics, University of North Carolina at Charlotte, Kannapolis, NC 28081, USA.
David C NorrisDepartment of Bioinformatics and Genomics, University of North Carolina at Charlotte, Kannapolis, NC 28081, USA.
Ann E LoraineDepartment of Bioinformatics and Genomics, University of North Carolina at Charlotte, Kannapolis, NC 28081, USA.

Funding

Integrated Genome Browser and IGB AppsR01GM103463 · NIGMS · UNIVERSITY OF NORTH CAROLINA CHARLOTTE · PI LORAINE, ANN E · 2012 to 2019
$2.7M
NIGMS NIH HHS R01 GM103463
6 · The paper itself

Abstract

motivationGenome browsers that support fast navigation through vast datasets and provide interactive visual analytics functions can help scientists achieve deeper insight into biological systems. Toward this end, we developed Integrated Genome Browser (IGB), a highly configurable, interactive and fast open source desktop genome browser.

resultsHere we describe multiple updates to IGB, including all-new capabilities to display and interact with data from high-throughput sequencing experiments. To demonstrate, we describe example visualizations and analyses of datasets from RNA-Seq, ChIP-Seq and bisulfite sequencing experiments. Understanding results from genome-scale experiments requires viewing the data in the context of reference genome annotations and other related datasets. To facilitate this, we enhanced IGB's ability to consume data from diverse sources, including Galaxy, Distributed Annotation and IGB-specific Quickload servers. To support future visualization needs as new genome-scale assays enter wide use, we transformed the IGB codebase into a modular, extensible platform for developers to create and deploy all-new visualizations of genomic data. AVAILABILITY AND IMPLEMENTATION: IGB is open source and is freely available from http://bioviz.org/igb CONTACT: aloraine@uncc.edu.

Indexed as

SoftwareAnimalsChromatin ImmunoprecipitationComputational BiologyGenomeGenomicsHigh-Throughput Nucleotide SequencingHumansSequence Analysis, RNAUser-Computer Interface

Identifiers

PMID27153568
PMCPMC4937187

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.