Evidence map›Paper›PMID 27153274›Full record

ArticleNature biotechnology2016

Production of hornless dairy cattle from genome-edited cell lines.

Daniel F Carlson, Cheryl A Lancto, Bin Zang, Eui-Soo Kim, Mark Walton, David Oldeschulte, Christopher Seabury, Tad S Sonstegard, Scott C Fahrenkrug

Abstract read
PubMed Publisher
In one paragraph

Article in Nature biotechnology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 120 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
120citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

120 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. The ethics of genome editing in non-human animals: a systematic review of reasons reported in the academic literature.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019
    Pooled it
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  13. Signature of Selection Analysis Reveals Candidate Genes Related to Climate Adaptation and Production Traits in Lao Native Goats.Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie · 2026
    Article
  14. Article
  15. Clinical outcome of an SCNT-derivedFrontiers in genome editing · 2026
    Article
  16. Article
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  18. Review
  19. Article
  20. Transgene Mapping in Animals: What to Choose?International journal of molecular sciences · 2025
    Review

60 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Daniel F CarlsonRecombinetics, St. Paul, Minnesota, USA.
Cheryl A LanctoRecombinetics, St. Paul, Minnesota, USA.
Bin ZangProgram in Scientific Computation, University of Minnesota, Minneapolis Minnesota, USA.
Eui-Soo KimRecombinetics, St. Paul, Minnesota, USA.
Mark WaltonRecombinetics, St. Paul, Minnesota, USA.
David OldeschulteDepartment of Veterinary Pathobiology, College of Veterinary Medicine, Texas A&M University, College Station, Texas, USA.ORCID 0000-0001-9704-7670
Christopher SeaburyDepartment of Veterinary Pathobiology, College of Veterinary Medicine, Texas A&M University, College Station, Texas, USA.
Tad S SonstegardRecombinetics, St. Paul, Minnesota, USA.
Scott C FahrenkrugRecombinetics, St. Paul, Minnesota, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAnimals, Genetically ModifiedCattleCell LineDairyingFemaleGene EditingGenetic EnhancementHorns

Identifiers

PMID27153274

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.