ReviewCurrent opinion in psychiatry2016
The natural history of substance use disorders.
Review in Current opinion in psychiatry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 40 citations in OpenAlex.
- Effect of serotonin receptor gene variants on substance use disorders.Annals of medicine · 2025Article
- The influence of dopamine receptor SNPs on substance use disorder in a Jordanian cohort.BMC research notes · 2025Article
- Investigating CHRNA5, CHRNA3, and CHRNB4 variants in the genetic landscape of substance use disorder in Jordan.BMC psychiatry · 2024Article
- Adverse Effects of Chewing Khat (Catha edulis): A Community-based Study in Ethiopia.Oman medical journal · 2023Article
- Family-Based Predictors of Alcohol Use Disorder (AUD) Recurrence and New Non-Alcohol Substance Use Disorder Onset Following Initial AUD Recovery.Journal of studies on alcohol and drugs · 2022Article
- Cannabis Use, Cannabis Use Disorder, and Comorbid Psychiatric Illness: A Narrative Review.Journal of clinical medicine · 2020Review
- History of opioid use as a risk factor for current use and mental health consequences among retired National Football League athletes: A 9-year follow-up investigation.Drug and alcohol dependence · 2020Article
- The Effectiveness ofThe Yale journal of biology and medicine · 2020Article
- Virtual Nature as an Intervention for Reducing Stress and Improving Mood in People with Substance Use Disorder.Journal of addiction · 2020Article
- Prediction of drug abuse recurrence: a Swedish National Study.Psychological medicine · 2018Article
- Stressful Events and Other Predictors of Remission from Drug Dependence in the United States: Longitudinal Results from a National Survey.Journal of substance abuse treatment · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
purpose of reviewIllicit drugs, alcohol, and tobacco use disorders contribute substantially to the global burden of disease. Knowledge about the major elements of the natural history of substance use disorders (incidence, remission, persistence, and relapse) is crucial to a broader understanding of the course and outcomes of substance use disorders. RECENT
findingsProspective cohort studies in nonclinical samples indicate that externalizing psychopathology in earlier life, including early disordered substance use, delinquency, and personality disorders, are related to substance use disorders later in life and chronic course. Externalizing psychopathology may be initiated by early adverse experiences, for example, childhood maltreatment and stressful life events. After controlling for confounders, 'age at first use' as a causal factor for alcohol use disorder later in life and the 'drug substitution' hypothesis are not supported in general population data. SUMMARY: Future research should focus on elaborating the causal framework that leads to the development and persistence of severe substance use disorders, with an emphasis on identifying modifiable factors for intervention by policy makers or health professionals. More research is needed on the natural history of substance use disorders in low-income and middle-income countries.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.