ArticleEnvironmental health perspectives2016
Ambient Fine Particulate Matter and Mortality among Survivors of Myocardial Infarction: Population-Based Cohort Study.
Article in Environmental health perspectives, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.
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Who cites it
36 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Long-Term PMJournal of the American Heart Association · 2021Pooled it
- Long-Term Exposure to Ambient Air Pollution and Myocardial Infarction: A Systematic Review and Meta-Analysis.Frontiers in medicine · 2021Pooled it
- Differential Association Between Surrounding Greenness and Mortality in Individuals With Coronary Heart Disease.JACC. Advances · 2026Article
- Article
- Machine learning prediction of STEMI incidence with SHAP interpretation of environmental determinants.Scientific reports · 2025Article
- Pharmacotherapeutic Strategies for Fine Particulate Matter-Induced Lung and Cardiovascular Damage: Marketed Drugs, Traditional Chinese Medicine, and Biological Agents.Cardiovascular toxicology · 2025Review
- The association between long-term PM2.5 exposure and risk for pancreatic cancer: an application of social informatics.American journal of epidemiology · 2025Article
- Air pollution and coronary atherosclerosis.Future cardiology · 2025Review
- Psychological repercussions of PM air pollution in human aging: a comprehensive review of urban and rural environments.Frontiers in pharmacology · 2025Review
- Combined Effect of Air Pollution and Genetic Risk on Incident Cardiovascular Diseases.Journal of the American Heart Association · 2024Article
- Particulate Matter-Induced Emerging Health Effects Associated with Oxidative Stress and Inflammation.Antioxidants (Basel, Switzerland) · 2024Review
- Long-term exposure to air pollution, greenness and temperature and survival after a nonfatal myocardial infarction.Environmental pollution (Barking, Essex : 1987) · 2024Article
- Particulate Matter Air Pollution and Long-Term Outcomes in Patients Undergoing Percutaneous Coronary Intervention.JACC. Advances · 2023Article
- Cigarette smoking and air pollution exposure and their effects on cardiovascular diseases.Frontiers in public health · 2023Review
- Chronic Exposure to Fine Particulate Matter Increases Mortality Through Pathways of Metabolic and Cardiovascular Disease: Insights From a Large Mediation Analysis.Journal of the American Heart Association · 2022Article
- Environmental risk factors and cardiovascular diseases: a comprehensive expert review.Cardiovascular research · 2022Article
- The Impact of Fine Particulate Matter 2.5 on the Cardiovascular System: A Review of the Invisible Killer.Nanomaterials (Basel, Switzerland) · 2022Review
- Joint associations between neighborhood walkability, greenness, and particulate air pollution on cardiovascular mortality among adults with a history of stroke or acute myocardial infarction.Environmental epidemiology (Philadelphia, Pa.) · 2022Article
- Long-term PMEnvironmental science and pollution research international · 2021Article
- Particulate Matter and Cardiovascular Risk in Adults with Chronic Obstructive Pulmonary Disease.American journal of respiratory and critical care medicine · 2021Article
Corrections and comments
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Authors and funding
13 authors.
Funding
Abstract
backgroundSurvivors of acute myocardial infarction (AMI) are at increased risk of dying within several hours to days following exposure to elevated levels of ambient air pollution. Little is known, however, about the influence of long-term (months to years) air pollution exposure on survival after AMI.
objectiveWe conducted a population-based cohort study to determine the impact of long-term exposure to fine particulate matter ≤ 2.5 μm in diameter (PM2.5) on post-AMI survival.
methodsWe assembled a cohort of 8,873 AMI patients who were admitted to 1 of 86 hospital corporations across Ontario, Canada in 1999-2001. Mortality follow-up for this cohort extended through 2011. Cumulative time-weighted exposures to PM2.5 were derived from satellite observations based on participants' annual residences during follow-up. We used standard and multilevel spatial random-effects Cox proportional hazards models and adjusted for potential confounders.
resultsBetween 1999 and 2011, we identified 4,016 nonaccidental deaths, of which 2,147 were from any cardiovascular disease, 1,650 from ischemic heart disease, and 675 from AMI. For each 10-μg/m3 increase in PM2.5, the adjusted hazard ratio (HR10) of nonaccidental mortality was 1.22 [95% confidence interval (CI): 1.03, 1.45]. The association with PM2.5 was robust to sensitivity analyses and appeared stronger for cardiovascular-related mortality: ischemic heart (HR10 = 1.43; 95% CI: 1.12, 1.83) and AMI (HR10 = 1.64; 95% CI: 1.13, 2.40). We estimated that 12.4% of nonaccidental deaths (or 497 deaths) could have been averted if the lowest measured concentration in an urban area (4 μg/m3) had been achieved at all locations over the course of the study.
conclusionsLong-term air pollution exposure adversely affects the survival of AMI patients. CITATION: Chen H, Burnett RT, Copes R, Kwong JC, Villeneuve PJ, Goldberg MS, Brook RD, van Donkelaar A, Jerrett M, Martin RV, Brook JR, Kopp A, Tu JV. 2016. Ambient fine particulate matter and mortality among survivors of myocardial infarction: population-based cohort study. Environ Health Perspect 124:1421-1428; http://dx.doi.org/10.1289/EHP185.
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