Evidence map›Paper›PMID 27152711›Full record

ArticleJournal of the American Chemical Society2016

A Versatile and Scalable Strategy to Discrete Oligomers.

Jimmy Lawrence, Sang-Ho Lee, Allison Abdilla, Mitchell D Nothling, Jing M Ren, Abigail S Knight, Carolin Fleischmann, Youli Li, Austin S Abrams, Bernhard V K J Schmidt and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Chemical Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 141 citations in OpenAlex.

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  7. Discrete Brush Polymers EnhanceJournal of the American Chemical Society · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 3 countries.

Jimmy LawrenceMaterials Research Laboratory and Departments of Materials, Chemistry and Biochemistry, University of California , Santa Barbara, California 93106, United States.
Sang-Ho LeeMaterials Research Laboratory and Departments of Materials, Chemistry and Biochemistry, University of California , Santa Barbara, California 93106, United States.
Allison AbdillaMaterials Research Laboratory and Departments of Materials, Chemistry and Biochemistry, University of California , Santa Barbara, California 93106, United States.
Mitchell D NothlingMaterials Research Laboratory and Departments of Materials, Chemistry and Biochemistry, University of California , Santa Barbara, California 93106, United States.
Jing M RenMaterials Research Laboratory and Departments of Materials, Chemistry and Biochemistry, University of California , Santa Barbara, California 93106, United States.
Abigail S KnightMaterials Research Laboratory and Departments of Materials, Chemistry and Biochemistry, University of California , Santa Barbara, California 93106, United States.
Carolin FleischmannMaterials Research Laboratory and Departments of Materials, Chemistry and Biochemistry, University of California , Santa Barbara, California 93106, United States.
Youli LiMaterials Research Laboratory and Departments of Materials, Chemistry and Biochemistry, University of California , Santa Barbara, California 93106, United States.
Austin S AbramsMaterials Research Laboratory and Departments of Materials, Chemistry and Biochemistry, University of California , Santa Barbara, California 93106, United States.
Bernhard V K J SchmidtMaterials Research Laboratory and Departments of Materials, Chemistry and Biochemistry, University of California , Santa Barbara, California 93106, United States.
Michael C HawkerMaterials Research Laboratory and Departments of Materials, Chemistry and Biochemistry, University of California , Santa Barbara, California 93106, United States.
Luke A ConnalDepartment of Chemical Engineering, University of Melbourne , Melbourne, Victoria, Australia.
Alaina J McGrathMaterials Research Laboratory and Departments of Materials, Chemistry and Biochemistry, University of California , Santa Barbara, California 93106, United States.
Paul G ClarkThe Dow Chemical Company, Midland, Michigan 48674, United States.
Will R GutekunstMaterials Research Laboratory and Departments of Materials, Chemistry and Biochemistry, University of California , Santa Barbara, California 93106, United States.
Craig J HawkerMaterials Research Laboratory and Departments of Materials, Chemistry and Biochemistry, University of California , Santa Barbara, California 93106, United States.
University of California, Santa Barbara · USUniversity of Melbourne · AUDow Chemical (United States) · USMax Planck Institute of Colloids and Interfaces · DE

Funding

Development of Sequence Controlled Polymers for Antibacterial Therapeutics and CoF32GM108323 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI GUTEKUNST, WILL RYAN · 2013 to 2015
$143k
NIGMS NIH HHS F32 GM108323
6 · The paper itself

Abstract

A versatile strategy is reported for the multigram synthesis of discrete oligomers from commercially available monomer families, e.g., acrylates, styrenics, and siloxanes. Central to this strategy is the identification of reproducible procedures for the separation of oligomer mixtures using automated flash chromatography systems with the effectiveness of this approach demonstrated through the multigram preparation of discrete oligomer libraries (Đ = 1.0). Synthetic availability, coupled with accurate structural control, allows these functional building blocks to be harnessed for both fundamental studies as well as targeted technological applications.

Indexed as

ChromatographyChromatography, GelChromatography, Thin LayerPolymersReproducibility of ResultsSmall Molecule LibrariesSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationPolymersSmall Molecule Libraries

Identifiers

PMID27152711
PMCPMC4879877
OpenAlexW2347029936

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.