Evidence map›Paper›PMID 27152673›Full record

ReviewChemical Society reviews2016

Design of virus-based nanomaterials for medicine, biotechnology, and energy.

Amy M Wen, Nicole F Steinmetz

Abstract readReview
In one paragraph

Review in Chemical Society reviews, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 129 papers.

0numbers the graph read from it
0cells of the map it votes in
129citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

129 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Plant-Derived Anti-Cancer Therapeutics and Biopharmaceuticals.Bioengineering (Basel, Switzerland) · 2024
    Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review

69 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Amy M WenDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106, USA. nicole.steinmetz@case.edu.
Nicole F SteinmetzDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106, USA. nicole.steinmetz@case.edu and Department of Radiology, Case Western Reserve University, Cleveland, OH 44106, USA and Department of Materials Science and Engineering, Case Western Reserve University, Cleveland, OH 44106, USA and Department of Macromolecular Science and Engineering, Case Western Reserve University, Cleveland, OH 44106, USA and Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH 44106, USA.

Funding

Diagnosis and longitudinal monitoring of metastatic prostate cancer through molecular MR imaging.R01CA202814 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI STEINMETZ, NICOLE FRANZISKA · 2016 to 2020
$2.0M
Detection of lethal prostate cancer with macromolecule-based, EGFL-7 targeted MR imaging approachR21EB020946 · NIBIB · CASE WESTERN RESERVE UNIVERSITY · PI STEINMETZ, NICOLE FRANZISKA · 2015 to 2016
$433k
Drug Delivery to Thrombotic Cardiovascular DiseaseR21HL121130 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI STEINMETZ, NICOLE FRANZISKA · 2015 to 2016
$416k
Engineering 'Grapevine Virus A' filaments for nanomedical applicationsR03EB020602 · NIBIB · CASE WESTERN RESERVE UNIVERSITY · PI STEINMETZ, NICOLE FRANZISKA · 2015 to 2016
$159k
Hemostasis-Independent targeted treatment of thrombosisF31HL129703 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI WEN, AMY · 2015 to 2015
$13k
NCI NIH HHS R01 CA202814NHLBI NIH HHS F31 HL129703NHLBI NIH HHS R21 HL121130NIBIB NIH HHS R03 EB020602NIBIB NIH HHS R21 EB020946
6 · The paper itself

Abstract

This review provides an overview of recent developments in "chemical virology." Viruses, as materials, provide unique nanoscale scaffolds that have relevance in chemical biology and nanotechnology, with diverse areas of applications. Some fundamental advantages of viruses, compared to synthetically programmed materials, include the highly precise spatial arrangement of their subunits into a diverse array of shapes and sizes and many available avenues for easy and reproducible modification. Here, we will first survey the broad distribution of viruses and various methods for producing virus-based nanoparticles, as well as engineering principles used to impart new functionalities. We will then examine the broad range of applications and implications of virus-based materials, focusing on the medical, biotechnology, and energy sectors. We anticipate that this field will continue to evolve and grow, with exciting new possibilities stemming from advancements in the rational design of virus-based nanomaterials.

Indexed as

VirusesAgricultureBiotechnologyDrug Delivery SystemsGenetic EngineeringGene Transfer TechniquesHumansImmunotherapyNanomedicineNanostructuresNanotechnology

Identifiers

PMID27152673
PMCPMC5068136

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.