Evidence map›Paper›PMID 27152321›Full record

ArticleACS infectious diseases2016

Plantazolicin is an ultra-narrow spectrum antibiotic that targets the

Katie J Molohon, Patricia M B Saint-Vincent, Seongjin Park, James R Doroghazi, Tucker Maxson, Jeremy R Hershfield, Kristen M Flatt, Nathan E Schroeder, Taekjip Ha, Douglas A Mitchell

Abstract read
In one paragraph

Article in ACS infectious diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 58 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Enterolyin S, a Polythiazole-containing Hemolytic Peptide from Enterococcus caccae.Chembiochem : a European journal of chemical biology · 2024
    Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. AntimicrobialAntibiotics (Basel, Switzerland) · 2022
    Review
  18. Article
  19. Article
  20. Listeriolysin S: A bacteriocin fromProceedings of the National Academy of Sciences of the United States of America · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Katie J MolohonDepartment of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801; Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801.
Patricia M B Saint-VincentDepartment of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801.
Seongjin ParkDepartment of Physics and Center for the Physics of Living Cells, University of Illinois at Urbana-Champaign, Urbana, IL 61801.
James R DoroghaziCarl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801.
Tucker MaxsonDepartment of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801.
Jeremy R HershfieldBacteriology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD 21702.
Kristen M FlattDepartment of Crop Sciences, University of Illinois at Urbana-Champaign, Urbana, IL 61801.
Nathan E SchroederDepartment of Crop Sciences, University of Illinois at Urbana-Champaign, Urbana, IL 61801.
Taekjip HaDepartment of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801; Department of Physics and Center for the Physics of Living Cells, University of Illinois at Urbana-Champaign, Urbana, IL 61801; Howard Hughes Medical Institute, Chevy Chase, MD 20815.
Douglas A MitchellDepartment of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801; Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801.
University of Illinois Urbana-Champaign · USUnited States Army Medical Research Institute of Infectious Diseases · US

Funding

Enzyme Chemistry and Biological Function of RiPP-like Modifications.R01GM097142 · NIGMS · VANDERBILT UNIVERSITY · PI MITCHELL, DOUGLAS ALAN · 2012 to 2024
$4.1M
Stress-induced phenotypic plasticity in C. elegansR01GM111566 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI SCHROEDER, NATHAN · 2014 to 2018
$1.4M
NIGMS NIH HHS R01 GM097142NIGMS NIH HHS R01 GM111566
6 · The paper itself

Abstract

Plantazolicin (PZN) is a ribosomally synthesized and post-translationally modified natural product from

Indexed as

anthraxantibioticBacillus anthracismembrane depolarizationmode of actionoxazolepathogen specific antibioticRibosomally synthesized and post-translationally modified natural productthiazole

Identifiers

PMID27152321
PMCPMC4852872
OpenAlexW2232566097

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.