Evidence map›Paper›PMID 27152278›Full record

ArticleAnnals of rehabilitation medicine2016

Survey of Botulinum Toxin Injections in Anticoagulated Patients: Korean Physiatrists' Preference in Controlling Anticoagulation Profile Prior to Intramuscular Injection.

Yongjun Jang, Geun-Young Park, Jihye Park, Asayeon Choi, Soo Yeon Kim, Chris Boulias, Chetan P Phadke, Farooq Ismail, Sun Im

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Annals of rehabilitation medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Dry Needling and Antithrombotic Drugs.Pain research & management · 2022
    Review
  2. Article
  3. Botulinum toxin therapy in patients with oral anticoagulation: is it safe?Journal of neural transmission (Vienna, Austria : 1996) · 2018
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Yongjun JangDepartment of Rehabilitation Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Geun-Young ParkDepartment of Rehabilitation Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Jihye ParkDepartment of Rehabilitation Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Asayeon ChoiDepartment of Rehabilitation Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Soo Yeon KimDepartment of Rehabilitation Medicine, Pusan National University School of Medicine, Busan, Korea.; Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, Korea.
Chris BouliasSpasticity Research Program, West Park Healthcare Centre, Toronto, Canada.; Division of Physiatry, Department of Medicine, University of Toronto, Toronto, Canada.
Chetan P PhadkeSpasticity Research Program, West Park Healthcare Centre, Toronto, Canada.; Division of Physiatry, Department of Medicine, University of Toronto, Toronto, Canada.; Faculty of Health, York University, Toronto, Canada.
Farooq IsmailSpasticity Research Program, West Park Healthcare Centre, Toronto, Canada.; Division of Physiatry, Department of Medicine, University of Toronto, Toronto, Canada.
Sun ImDepartment of Rehabilitation Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Catholic University of Korea · KRUniversity of Toronto · CAPusan National University Yangsan Hospital · KRWest Park Healthcare Centre · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate Korean physiatrists' practice of performing intramuscular botulinum toxin injection in anticoagulated patients and to assess their preference in controlling the bleeding risk before injection.

methodsAs part of an international collaboration survey study, a questionnaire survey was administered to 100 Korean physiatrists. Physiatrists were asked about their level of experience with botulinum toxin injection, the safe international normalized ratio range in anticoagulated patients undergoing injection, their tendency for injecting into deep muscles, and their experience of bleeding complications.

resultsInternational normalized ratio <2.0 was perceived as an ideal range for performing Botulinum toxin injection by 41% of the respondents. Thirty-six respondents replied that the international normalized ratio should be lowered to sub-therapeutic levels before injection, and 18% of the respondents reported that anticoagulants should be intentionally withheld and discontinued prior to injection. In addition, 20%-30% of the respondents answered that they were uncertain whether they should perform the injection regardless of the international normalized ratio values. About 69% of the respondents replied that they did have any standardized protocols for performing botulinum toxin injection in patients using anticoagulants. Only 1 physiatrist replied that he had encountered a case of compartment syndrome.

conclusionIn accordance with the lack of consensus in performing intramuscular botulinum toxin injection in anticoagulated patients, our survey shows a wide range of practices among many Korean physiatrists; they tend to avoid botulinum toxin injection in anticoagulated patients and are uncertain about how to approach these patients. The results of this study emphasize the need for formulating a proper international consensus on botulinum toxin injection management in anticoagulated patients.

Indexed as

AnticoagulantsBotulinum toxinsInternational normalized ratioIntramuscular injections

Identifiers

PMID27152278
PMCPMC4855122
OpenAlexW4234302172

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.