ReviewInternational journal of obesity supplements2015
Thermogenic potential and physiological relevance of human epicardial adipose tissue.
Review in International journal of obesity supplements, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 31 citations in OpenAlex.
- Association of epicardial fat tissue combined with left ventricular strain with left ventricular fibrosis in obese patients: a cardiac magnetic resonance study.Quantitative imaging in medicine and surgery · 2026Article
- Heart matters: How glucose- and lipid-modulating drugs remodel epicardial adipose tissue accumulation, inflammatory patterns and browning.Diabetes, obesity & metabolism · 2026Review
- Impact of epicardial adipose tissue on myocardial function and structure in patients with severe aortic valve stenosis.ESC heart failure · 2025Article
- The interplay of inflammation, exosomes and CaCardiovascular diabetology · 2023Review
- LSD1 in beige adipocytes protects cardiomyocytes against oxygen and glucose deprivation.Iranian journal of basic medical sciences · 2023Article
- The role of epicardial adipose tissue dysfunction in cardiovascular diseases: an overview of pathophysiology, evaluation, and management.Frontiers in endocrinology · 2023Review
- Profiling of Non-Coding Regulators and Their Targets in Epicardial Fat from Patients with Coronary Artery Disease.International journal of molecular sciences · 2022Article
- Epicardial and pericardial fat analysis on CT images and artificial intelligence: a literature review.Quantitative imaging in medicine and surgery · 2022Review
- Article
- Susceptibilities of epicardial and subcutaneous fat tissue for browning-gene expression and diet-induced volume reduction are different.Molecular medicine reports · 2018Article
- The Isolation and Culture of Primary Epicardial Cells Derived from Human Adult and Fetal Heart Specimens.Journal of visualized experiments : JoVE · 2018Article
- Article
- Functional characterization of the Ucp1-associated oxidative phenotype of human epicardial adipose tissue.Scientific reports · 2017Article
- Investigating interactions between epicardial adipose tissue and cardiac myocytes: what can we learn from different approaches?British journal of pharmacology · 2017Review
- Regulation of Brown Adipose Tissue Activity by Interoceptive CNS Pathways: The interaction between Brain and Periphery.Frontiers in neuroscience · 2017Article
- The Flexibility of Ectopic Lipids.International journal of molecular sciences · 2016Review
- Physiological determinants and impacts of the adipocyte phenotype.International journal of obesity supplements · 2015Article
- Hypothalamic control of brown adipose tissue thermogenesis.Frontiers in systems neuroscience · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Epicardial adipose tissue is a unique fat depot around the heart that shares a close anatomic proximity and vascular supply with the myocardium and coronary arteries. Its accumulation around the heart, measured using various imaging modalities, has been associated with the onset and progression of coronary artery disease in humans. Epicardial adipose tissue is also the only fat depot around the heart that is known to express uncoupling protein 1 at both mRNA and protein levels in the detectable range. Recent advances have further indicated that human epicardial fat exhibits beige fat-like features. Here we provide an overview of the physiological and pathophysiological relevance of human epicardial fat, and further discuss whether its thermogenic properties can serve as a target for the therapeutic management of coronary heart disease in humans.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.