Evidence map›Paper›PMID 27152146›Full record

ArticleJournal of biomedical semantics2016

The Non-Coding RNA Ontology (NCRO): a comprehensive resource for the unification of non-coding RNA biology.

Jingshan Huang, Karen Eilbeck, Barry Smith, Judith A Blake, Dejing Dou, Weili Huang, Darren A Natale, Alan Ruttenberg, Jun Huan, Michael T Zimmermann and 10 more

Abstract read
In one paragraph

Article in Journal of biomedical semantics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Jingshan HuangSchool of Computing, University of South Alabama, Mobile, Alabama, 36688-0002 USA.
Karen EilbeckDepartment of Biomedical Informatics, University of Utah, Salt Lake City, 84112-5775 Utah USA.
Barry SmithDepartment of Philosophy, University at Buffalo, Buffalo, 14260-4150 New York USA.
Judith A BlakeGenome Informatics, The Jackson Laboratory, Bar Harbor, Maine, 04609-1523 USA.
Dejing DouComputer and Information Science Department, University of Oregon, Eugene, Oregon, 97403-1202 USA.
Weili HuangMiracle Query, Inc., Eugene, Oregon, 97403-1202 USA.
Darren A NataleDepartment of Biochemistry and Molecular & Cellular Biology, Georgetown University Medical Center, Washington D.C., 20007-1485 USA.
Alan RuttenbergSchool of Dental Medicine, University at Buffalo, Buffalo, 14214-8006 New York USA.
Jun HuanDepartment of Electrical Engineering and Computer Science, University of Kansas, Lawrence, 66047-7621 Kansas USA.
Michael T ZimmermannHealth Sciences Research, Division of Biomedical Statistics and Informatics, Mayo Clinic College of Medicine, Rochester, 55905-0001 Minnesota USA.
Guoqian JiangHealth Sciences Research, Division of Biomedical Statistics and Informatics, Mayo Clinic College of Medicine, Rochester, 55905-0001 Minnesota USA.
Yu LinCenter for Computational Science, University of Miami, Miami, 33146-2960 Florida USA.
Bin WuDepartment of Microbiology & Immunology, First Affiliated Hospital, Kunming Medical University, Kunming, Yunnan, 650032 China.
Harrison J StrachanSchool of Computing, University of South Alabama, Mobile, Alabama, 36688-0002 USA.
Yongqun HeDepartment of Microbiology & Immunology, University of Michigan Medical School, Ann Arbor, Michigan, 48109-5624 USA.
Shaojie ZhangDepartment of Computer Science, University of Central Florida, Orlando, 32816-2362 Florida USA.
Xiaowei WangDepartment of Radiation Oncology, Washington University School of Medicine, St. Louis, Missouri, 63110-0001 USA.
Zixing LiuMitchell Cancer Institute, University of South Alabama, Mobile, Alabama, 36604-1405 USA.
Glen M BorchertDepartment of Biology, University of South Alabama, Mobile, Alabama, 36688-0002 USA.
Ming TanMitchell Cancer Institute, University of South Alabama, Mobile, Alabama, 36604-1405 USA.

Funding

PRO: A Protein Ontology in Open Biomedical OntologiesR01GM080646 · NIGMS · UNIVERSITY OF DELAWARE · PI WU, CATHY H. · 2007 to 2018
$8.9M
OmniSearch: A semantic search tool for discovering microRNAs' critical roles in hU01CA180982 · NCI · UNIVERSITY OF SOUTH ALABAMA · PI HUANG, JINGSHAN · 2014 to 2016
$913k
NCI NIH HHS U01 CA180982NIGMS NIH HHS R01 GM080646
6 · The paper itself

Abstract

In recent years, sequencing technologies have enabled the identification of a wide range of non-coding RNAs (ncRNAs). Unfortunately, annotation and integration of ncRNA data has lagged behind their identification. Given the large quantity of information being obtained in this area, there emerges an urgent need to integrate what is being discovered by a broad range of relevant communities. To this end, the Non-Coding RNA Ontology (NCRO) is being developed to provide a systematically structured and precisely defined controlled vocabulary for the domain of ncRNAs, thereby facilitating the discovery, curation, analysis, exchange, and reasoning of data about structures of ncRNAs, their molecular and cellular functions, and their impacts upon phenotypes. The goal of NCRO is to serve as a common resource for annotations of diverse research in a way that will significantly enhance integrative and comparative analysis of the myriad resources currently housed in disparate sources. It is our belief that the NCRO ontology can perform an important role in the comprehensive unification of ncRNA biology and, indeed, fill a critical gap in both the Open Biological and Biomedical Ontologies (OBO) Library and the National Center for Biomedical Ontology (NCBO) BioPortal. Our initial focus is on the ontological representation of small regulatory ncRNAs, which we see as the first step in providing a resource for the annotation of data about all forms of ncRNAs. The NCRO ontology is free and open to all users, accessible at: http://purl.obolibrary.org/obo/ncro.owl.

Indexed as

Biological OntologiesRNA, UntranslatedRNA, UntranslatedBiomedical ontologyData annotationDomain ontologyNon-coding RNAOntology developmentReference ontology

Identifiers

PMID27152146
PMCPMC4857245

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.