Evidence map›Paper›PMID 27152138›Full record

ArticleWorld journal of gastrointestinal surgery2016

Over-the-scope clips in the treatment of gastrointestinal tract iatrogenic perforation: A multicenter retrospective study and a classification of gastrointestinal tract perforations.

Benedetto Mangiavillano, Angelo Caruso, Raffaele Manta, Roberto Di Mitri, Alberto Arezzo, Nico Pagano, Giuseppe Galloro, Filippo Mocciaro, Massimiliano Mutignani, Carmelo Luigiano and 3 more

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastrointestinal surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Endoscopic closure of full-thickness transverse colon perforation with sequential over-the-scope clips including retroflexed deployment.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Benedetto MangiavillanoBenedetto Mangiavillano, Gastroenterology and Gastrointestinal Endoscopy, Borea Hospital, 18038 Sanremo, Italy.
Angelo CarusoBenedetto Mangiavillano, Gastroenterology and Gastrointestinal Endoscopy, Borea Hospital, 18038 Sanremo, Italy.
Raffaele MantaBenedetto Mangiavillano, Gastroenterology and Gastrointestinal Endoscopy, Borea Hospital, 18038 Sanremo, Italy.
Roberto Di MitriBenedetto Mangiavillano, Gastroenterology and Gastrointestinal Endoscopy, Borea Hospital, 18038 Sanremo, Italy.
Alberto ArezzoBenedetto Mangiavillano, Gastroenterology and Gastrointestinal Endoscopy, Borea Hospital, 18038 Sanremo, Italy.
Nico PaganoBenedetto Mangiavillano, Gastroenterology and Gastrointestinal Endoscopy, Borea Hospital, 18038 Sanremo, Italy.
Giuseppe GalloroBenedetto Mangiavillano, Gastroenterology and Gastrointestinal Endoscopy, Borea Hospital, 18038 Sanremo, Italy.
Filippo MocciaroBenedetto Mangiavillano, Gastroenterology and Gastrointestinal Endoscopy, Borea Hospital, 18038 Sanremo, Italy.
Massimiliano MutignaniBenedetto Mangiavillano, Gastroenterology and Gastrointestinal Endoscopy, Borea Hospital, 18038 Sanremo, Italy.
Carmelo LuigianoBenedetto Mangiavillano, Gastroenterology and Gastrointestinal Endoscopy, Borea Hospital, 18038 Sanremo, Italy.
Enrico AntonucciBenedetto Mangiavillano, Gastroenterology and Gastrointestinal Endoscopy, Borea Hospital, 18038 Sanremo, Italy.
Rita ConigliaroBenedetto Mangiavillano, Gastroenterology and Gastrointestinal Endoscopy, Borea Hospital, 18038 Sanremo, Italy.
Enzo MasciBenedetto Mangiavillano, Gastroenterology and Gastrointestinal Endoscopy, Borea Hospital, 18038 Sanremo, Italy.
Ospedale L. Bonomo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo determine the outcome of the management of iatrogenic gastrointestinal tract perforations treated by over-the-scope clip (OTSC) placement.

methodsWe retrospectively enrolled 20 patients (13 female and 7 male; mean age: 70.6 ± 9.8 years) in eight high-volume tertiary referral centers with upper or lower iatrogenic gastrointestinal tract perforation treated by OTSC placement. Gastrointestinal tract perforation could be with oval-shape or with round-shape. Oval-shape perforations were closed by OTSC only by suction and the round-shape by the "twin-grasper" plus suction.

resultsMain perforation diameter was 10.1 ± 4.3 mm (range 3-18 mm). The technical success rate was 100% (20/20 patients) and the clinical success rate was 90% (18/20 patients). Two patients (10%) who did not have complete sealing of the defect underwent surgery. Based upon our observations we propose two types of perforation: Round-shape "type-1 perforation" and oval-shape "type-2 perforation". Eight (40%) out of the 20 patients had a type-1 perforation and 12 patients a type-2 (60%).

conclusionOTSC placement should be attempted after perforation occurring during diagnostic or therapeutic endoscopy. A failed closure attempt does not impair subsequent surgical treatment.

Indexed as

Gastrointestinal tractOver-the-scope clipOVESCOPerforation

Identifiers

PMID27152138
PMCPMC4840171
OpenAlexW2337772147

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.