Evidence map›Paper›PMID 27152043›Full record

ArticleThe Canadian veterinary journal = La revue veterinaire canadienne2016

Serum antibody responses to vaccinal antigens in lean and obese geriatric dogs.

John Ellis, Sheryl Gow, Carrie Rhodes, Stacey Lacoste, Lyndsay Kong, Kristyna Musil, Elisabeth Snead

Open access · greenAbstract read
In one paragraph

Article in The Canadian veterinary journal = La revue veterinaire canadienne, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Development of Dog Immune System: FromVeterinary sciences · 2019
    Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

John EllisDepartments of Veterinary Microbiology (Ellis, Rhodes, Lacoste), Large Animal Clinical Sciences (Gow), and Small Animal Clinical Sciences (Kong, Musil, Snead), Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4.
Sheryl GowDepartments of Veterinary Microbiology (Ellis, Rhodes, Lacoste), Large Animal Clinical Sciences (Gow), and Small Animal Clinical Sciences (Kong, Musil, Snead), Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4.
Carrie RhodesDepartments of Veterinary Microbiology (Ellis, Rhodes, Lacoste), Large Animal Clinical Sciences (Gow), and Small Animal Clinical Sciences (Kong, Musil, Snead), Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4.
Stacey LacosteDepartments of Veterinary Microbiology (Ellis, Rhodes, Lacoste), Large Animal Clinical Sciences (Gow), and Small Animal Clinical Sciences (Kong, Musil, Snead), Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4.
Lyndsay KongDepartments of Veterinary Microbiology (Ellis, Rhodes, Lacoste), Large Animal Clinical Sciences (Gow), and Small Animal Clinical Sciences (Kong, Musil, Snead), Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4.
Kristyna MusilDepartments of Veterinary Microbiology (Ellis, Rhodes, Lacoste), Large Animal Clinical Sciences (Gow), and Small Animal Clinical Sciences (Kong, Musil, Snead), Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4.
Elisabeth SneadDepartments of Veterinary Microbiology (Ellis, Rhodes, Lacoste), Large Animal Clinical Sciences (Gow), and Small Animal Clinical Sciences (Kong, Musil, Snead), Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4.
University of Saskatchewan · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The immune responses in control dogs [1 to 4 years of age, body condition score (BCS): 4 to 5 out of 9] were compared to those of aging dogs (based on breed and body size) either categorized as lean (BCS: 4 to 5 out of 9) or obese (BCS: 8 to 9 out of 9). Of interest were the serum titers to the following common agents found in vaccines, canine parainfluenza virus (CPIV), canine parvovirus (CPV), canine distemper virus (CDV), canine respiratory coronavirus (CRCoV), and Bordetella bronchiseptica. There were no statistical differences in the antibodies to CPIV, B. bronchispetica, and CRCoV, among the age/weight categories, nor among the age/weight categories and the time, in days, between the date of sample collection and the date of the last recorded vaccination for CPIV, B. bronchiseptica, CPV, and CDV. For CPV, the control dogs had significantly (P < 0.002) higher serum neutralization (SN) titers than the lean geriatric dogs and the obese geriatric dogs. For CDV SN titers, the only statistically significant (P = 0.01) difference was that the control dogs had higher SN titers than the lean geriatric dogs.

Indexed as

AgingAnimalsAntibodies, NeutralizingAntibodies, ViralDogsImmunogenicity, VaccineObesityThinnessViral VaccinesAntibodies, NeutralizingAntibodies, ViralViral Vaccines

Identifiers

PMID27152043
PMCPMC4827746
OpenAlexW2397314844

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.