Trial reportJournal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine2016
Prediction of Spontaneous Preterm Birth Among Nulliparous Women With a Short Cervix.
Trial report in Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Diagnosis or prognosis? An umbrella review of mid-trimester cervical length and spontaneous preterm birth.BJOG : an international journal of obstetrics and gynaecology · 2023Pooled it
- A new perspective on predicting latency period in preterm premature rupture of membranes: the role of cervical area measurement.Irish journal of medical science · 2026Article
- External validation of QUiPP App in three independent European cohorts of symptomatic women.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2025Article
- Prediction of preterm birth using machine learning: a comprehensive analysis based on large-scale preschool children survey data in Shenzhen of China.BMC pregnancy and childbirth · 2024Article
- Prediction of preterm birth in multiparous women using logistic regression and machine learning approaches.Scientific reports · 2024Article
- Changing Indications for Cervical Cerclage Following the Introduction of Routine Ultrasound Surveillance of Cervical Length for Prediction and Prevention of Preterm Birth.International journal of women's health · 2024Article
- Timing of antenatal steroid administration for imminent preterm birth: results of a prospective observational study in Germany.Archives of gynecology and obstetrics · 2023Observational
- Association Between Cervical Cancer Screening Guidelines and Preterm Delivery Among Females Aged 18 to 24 Years.JAMA health forum · 2023Article
- Predicting Preterm Birth with Strain Ratio Analysis of the Internal Cervical Os: A Prospective Study.Journal of clinical medicine · 2023Article
- Maternal preterm birth prediction in the United States: a case-control database study.BMC pediatrics · 2022Article
- A Timely Administration of Antenatal Steroids Is Highly Protective Against Intraventricular Hemorrhage: An Observational Multicenter Cohort Study of Very Low Birth Weight Infants.Frontiers in pediatrics · 2022Article
- The Effects of Preterm Birth on Musculoskeletal Health-Related Disorders.Journal of clinical medicine · 2021Review
- Prediction of Spontaneous Preterm Birth in At-risk Women Using Thrombospondin 1 from Cervicovaginal Fluid: A Prospective Observational Study.Geburtshilfe und Frauenheilkunde · 2021Article
- Clinical risk models for preterm birth less than 28 weeks and less than 32 weeks of gestation using a large retrospective cohort.Journal of perinatology : official journal of the California Perinatal Association · 2021Article
- Prediction of preterm birth in nulliparous women using logistic regression and machine learning.PloS one · 2021Article
- Serum Decorin, Biglycan, and Extracellular Matrix Component Expression in Preterm Birth.Reproductive sciences (Thousand Oaks, Calif.) · 2021Article
- Subsequent pregnancy outcomes according to the presence of acute histologic chorioamnionitis in women with spontaneous preterm delivery.Obstetrics & gynecology science · 2020Article
- Predicting preterm birth: Cervical length and fetal fibronectin.Seminars in perinatology · 2017Review
- Probing the potential of mucus permeability to signify preterm birth risk.Scientific reports · 2017Article
Corrections and comments
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Authors and funding
17 authors at 16 institutions in 1 country.
Funding
Abstract
objectivesThe purpose of this study was to evaluate whether demographic and sonographic factors associated with spontaneous preterm birth among nulliparous women with a cervical length of less than 30 mm could be combined into an accurate prediction model for spontaneous preterm birth.
methodsWe conducted a secondary analysis of a trial of nulliparous women with a singleton gestation and a cervical length of less than 30 mm on transvaginal sonography between 16 and 22 weeks who lacked other risk factors for spontaneous (eg, prior cervical excisional procedure) or medically indicated (eg, chronic hypertension) preterm birth, who were randomized to either 17α-hydroxyprogesterone caproate treatment or a placebo. Risk factors associated with spontaneous preterm birth within the entire cohort were identified by univariable analysis. Factors significantly associated (P < .05) with spontaneous preterm birth were included in a multivariable logistic regression analysis to determine whether an accurate prediction model could be developed.
resultsOf the 657 randomized patients, 109 (16.6%) had spontaneous preterm birth before 37 weeks' gestation. Logistic regression analysis revealed only cervical length (odds ratio, 1.06 per 1-mm decrease; 95% confidence interval, 1.02-1.10) to be associated with spontaneous preterm birth. The area under the receiver operating characteristic curve based on this regression was low (0.63; 95% confidence interval, 0.58-0.69). Results were similar for the outcome of spontaneous preterm birth before 34 weeks.
conclusionsAn accurate prediction model for spontaneous preterm birth among nulliparous women with a short cervix could not be developed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.