ReviewClinical journal of the American Society of Nephrology : CJASN2016
Climate Change and the Emergent Epidemic of CKD from Heat Stress in Rural Communities: The Case for Heat Stress Nephropathy.
Review in Clinical journal of the American Society of Nephrology : CJASN, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 209 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
209 citing papers in PubMed, 462 citations in OpenAlex.
- Acute sodium bicarbonate supplementation reduces the increase in markers of acute kidney injury during physical work in the heat.European journal of applied physiology · 2025Trial
- Exploring the effects of outdoor physical work in the heat, with or without sodium bicarbonate supplementation, on markers of acute kidney injury.Physiological reports · 2025Trial
- Rehydration effect of qingshu buye decoction on exercise and high temperature-induced dehydration.Journal of the International Society of Sports Nutrition · 2024Trial
- The Effect of Participatory Heat Education on Agricultural Worker Knowledge.Journal of agromedicine · 2023Trial
- Fructose increases risk for kidney stones: potential role in metabolic syndrome and heat stress.BMC nephrology · 2018Trial
- Increased Serum Sodium and Serum Osmolarity Are Independent Risk Factors for Developing Chronic Kidney Disease; 5 Year Cohort Study.PloS one · 2017Trial
- Study Protocol for the Daasanach Human Biology Project: A Longitudinal Study of the Impact of Drinking Water Salinity and Heat Stress on Water Insecurity, Hydration, Energetics, Hypertension, and Kidney Function in Northern Kenya.American journal of human biology : the official journal of the Human Biology Council · 2026Article
- Epidemiology, mechanisms and clinical implications of heat-related kidney disease.Nature reviews. Nephrology · 2026Review
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- Review
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- Artificial intelligence in nephrology: predicting CKD progression and personalizing treatment.International urology and nephrology · 2026Review
- Kidney health among adolescents living in a high-risk region for CKDu.BMC nephrology · 2026Article
- Occupational heat stress among female agricultural workers in the Jordan Valley, Palestine.Annals of work exposures and health · 2026Article
- Disparity in the regulation and prevention of water versus sodium imbalance in heat-stress nephropathy: a phylogenetic perspective.Clinical kidney journal · 2026Review
- Review
- Effects of social determinants of health on the landscape of kidney disease.Nature reviews. Nephrology · 2026Review
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- Kidney Health in a Warming World: Heat, Climate Change, and Implications for Care.Kidney international reports · 2026Article
- The Vulnerability and Resilience of Drinking Water Systems to Extreme Weather Events and Future Climate Change.Current environmental health reports · 2026Review
149 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
24 authors at 1 institution in 1 country.
Funding
Abstract
Climate change has led to significant rise of 0.8°C-0.9°C in global mean temperature over the last century and has been linked with significant increases in the frequency and severity of heat waves (extreme heat events). Climate change has also been increasingly connected to detrimental human health. One of the consequences of climate-related extreme heat exposure is dehydration and volume loss, leading to acute mortality from exacerbations of pre-existing chronic disease, as well as from outright heat exhaustion and heat stroke. Recent studies have also shown that recurrent heat exposure with physical exertion and inadequate hydration can lead to CKD that is distinct from that caused by diabetes, hypertension, or GN. Epidemics of CKD consistent with heat stress nephropathy are now occurring across the world. Here, we describe this disease, discuss the locations where it appears to be manifesting, link it with increasing temperatures, and discuss ongoing attempts to prevent the disease. Heat stress nephropathy may represent one of the first epidemics due to global warming. Government, industry, and health policy makers in the impacted regions should place greater emphasis on occupational and community interventions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.