ArticleScientific reports2016
The accommodative ciliary muscle function is preserved in older humans.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 41 citations in OpenAlex.
- In vivo biomechanical property detection of the ciliary muscle based on optical coherence tomography and digital image correlation technology.Eye and vision (London, England) · 2026Article
- Influence of Light Wavelength and Optotype Size on Accommodative Response and Aberrometric Changes Across the Adult Lifespan.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026Article
- Lens aging and disease: Molecular mechanisms, functional consequences, and pharmacological implications.Progress in retinal and eye research · 2026Review
- A protocol for management of presbyopia through ancient yogic eye purificatory method: A randomized controlled trial.Contemporary clinical trials communications · 2025Article
- Real-Time Control of a Focus Tunable Lens for Presbyopia Correction Using Ciliary Muscle Biopotentials and Artificial Neural Networks.Bioengineering (Basel, Switzerland) · 2025Article
- Non-invasive measuring of biopotentials of the ciliary muscle during accommodation in emmetropes.Scientific reports · 2025Article
- Quantitative fs-laser crystalline lens softening surgery towards presbyopia treatment based on optical coherence elastography.Biomedical optics express · 2025Article
- Article
- Ciliary muscle traction during accommodation is able to induce optic nerve head deformation.Eye (London, England) · 2025Article
- Biomechanical simulations of crystalline lens oscillations resulting from the changes in the gaze in an accommodated eye.Frontiers in bioengineering and biotechnology · 2025Article
- Estimation of the full shape of the crystalline lens from OCT: validation using stretched donor lenses.Biomedical optics express · 2023Article
- New technology using crystalline lens autofluorescence for presbyopia and cataract grading.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023Article
- Complexity of crystalline lens wobbling investigated by means of combined mechanical and optical simulations.Biomedical optics express · 2023Article
- Ultrahigh field MRI determination of water diffusion rates inQuantitative imaging in medicine and surgery · 2021Article
- Clinical performance of presbyopia correction with a multifocal corneoscleral lens.International journal of ophthalmology · 2021Article
- A Purkinje image-based system for an assessment of the density and transmittance spectra of the human crystalline lens in vivo.Scientific reports · 2020Article
- Difference in Pupillary Diameter as an Important Factor for Evaluating Amplitude of Accommodation: A Prospective Observational Study.Journal of clinical medicine · 2020Article
- Relationship of postsaccadic oscillation with the state of the pupil inside the iris and with cognitive processing.Journal of neurophysiology · 2020Article
- Semiautomatic procedure to assess changes in the eye accommodative system.International ophthalmology · 2018Article
- Effect of Yoga-Based Ocular Exercises in Lowering of Intraocular Pressure in Glaucoma Patients: An Affirmative Proposition.International journal of yogaArticle
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Presbyopia, the loss of the eye's accommodation capability, affects all humans aged above 45-50 years old. The two main reasons for this to happen are a hardening of the crystalline lens and a reduction of the ciliary muscle functionality with age. While there seems to be at least some partial accommodating functionality of the ciliary muscle at early presbyopic ages, it is not yet clear whether the muscle is still active at more advanced ages. Previous techniques used to visualize the accommodation mechanism of the ciliary muscle are complicated to apply in the older subjects, as they typically require fixation stability during long measurement times and/or to have an ultrasound probe directly in contact with the eye. Instead, we used our own developed method based on high-speed recording of lens wobbling to study the ciliary muscle activity in a small group of pseudophakic subjects (around 80 years old). There was a significant activity of the muscle, clearly able to contract under binocular stimulation of accommodation. This supports a purely lenticular-based theory of presbyopia and it might stimulate the search for new solutions to presbyopia by making use of the remaining contraction force still presented in the aging eye.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.