ArticleEye (London, England)2016
Elevated neutrophil-to-lymphocyte ratio in pseudoexfoliation syndrome.
Article in Eye (London, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Epidemiology, biometric features and risk factors of pseudoexfoliation syndrome among cataract patients: a hospital-based study in Apulia.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Pooled it
- Systemic Immune-Inflammation Index and Unconjugated Bilirubin Levels Are Associated with Pseudoexfoliation Syndrome.Journal of ophthalmic & vision research · 2025Article
- Hematological inflammation biomarkers in patients with pseudoexfoliation syndrome and pseudoexfoliation glaucoma.International journal of ophthalmology · 2025Article
- Predictive role of systemic immune-inflammation index and neutrophil/lymphocyte ratio values in infants with retinopathy of prematurity.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024Article
- Effect of Periodontitis on Dry Eye Disease Signs and Symptoms: A Cross-sectional Study.Oral health & preventive dentistry · 2024Article
- Inflammation and Neurodegeneration in Glaucoma: Isolated Eye Disease or a Part of a Systemic Disorder? - Serum Proteomic Analysis.Journal of inflammation research · 2024Article
- Complete Blood Cell Count-Derived Inflammation Biomarkers and the Need for Laser Capsulotomy Due to Posterior Capsule Opacification Following Cataract Surgery.Journal of inflammation research · 2024Article
- Impact of cardiovascular comorbidity on increased neutrophil-lymphocyte ratio in pseudoexfoliation syndrome.Medicine · 2022Article
- Neutrophil lymphocyte ratio as a predictor of perioperative complications in patients with PEX Syndrome during cataract surgery.International ophthalmology · 2022Article
- Relationship of Neutrophil-to-Lymphocyte and Platelet-to-Lymphocyte Ratio With Visual Acuity After Surgical Repair of Open Globe Injury.Frontiers in medicine · 2021Article
- Neutrophil-to-lymphocyte ratio in ocular diseases: a systematic review.International journal of ophthalmology · 2019Review
- Increased red cell distribution width levels in children with seasonal allergic conjunctivitis.International ophthalmology · 2018Article
- Elevated levels of plasma tumor necrosis factor alpha in patients with pseudoexfoliation glaucoma.Clinical ophthalmology (Auckland, N.Z.) · 2018Article
- Article
- The correlation of routine hematological indices with pterygium.Therapeutic advances in ophthalmologyArticle
- Systemic immuno-inflammatory index in patients with pseudoexfoliation syndrome and pseudoexfoliative glaucoma.Therapeutic advances in ophthalmologyArticle
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PurposeTo investigate the relationship between serum neutrophil/lymphocyte ratio and pseudoexfoliation syndrome.Materials and methodsThis study was designed as a retrospective analysis. Patients were divided into three groups: 55 patients with pseudoexfoliation syndrome (group 1), 19 patients with pseudoexfoliation glaucoma (group 2), and 48 control subjects without pseudoexfoliation syndrome or pseudoexfoliation glaucoma (group 3). The levels of neutrophils and lymphocytes were measured by ABX Pentra DF120/USA biochemical analyzer. The neutrophil/lymphocyte ratio was measured by dividing neutrophil count by lymphocyte count.ResultsThe mean ages of patients were 67.9±8.1 in group 1, 70.6±7.4 in group 2, and 67.3±7.6 in group 3 (P=0.172). Baseline clinical characteristics, such as diabetes and hypertension, were similar among groups. The mean neutrophil/lymphocyte ratio values were 2.08±0.61 in group 1, 2.20±0.58 in group 2, and 1.51±0.57 in group 3. The neutrophil/lymphocyte ratio was significantly higher in group 1 and 2 than the group 3 (P<0.001). In receiver operating characteristics analysis, the area under the curve for neutrophil/lymphocyte ratio was 0.776, and a neutrophil/lymphocyte ratio of >1.72 predicted pseudoexfoliation syndrome with a sensitivity of 77% and specificity of 71%.ConclusionThe elevated neutrophil/lymphocyte ratio is significantly associated with pseudoexfoliation syndrome. This novel and low-cost parameter can provide useful information for the relevant risk evaluation in these patients.
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