Evidence map›Paper›PMID 27151531›Full record

ArticleCirculation2016

Electrophysiological Effects of Selective Atrial Coronary Artery Occlusion in Humans.

Jesús Álvarez-García, Miquel Vives-Borrás, Pedro Gomis, Jordi Ordoñez-Llanos, Andreu Ferrero-Gregori, Antoni Serra-Peñaranda, Juan Cinca

Open access · greenAbstract read
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In one paragraph

Article in Circulation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 52 citations in OpenAlex.

  1. Trial
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  4. Review
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  6. Article
  7. Association between obesity and cardiac conduction defects.Frontiers in cardiovascular medicine · 2025
    Article
  8. Observational
  9. Review
  10. Conduction Disorders in the Setting of Acute STEMI.Current cardiology reviews · 2021
    Review
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  12. Article
  13. Observational
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jesús Álvarez-GarcíaFrom Cardiology Department, Hospital de la Santa Creu i Sant Pau, IIB-SantPau, Universidad Autónoma de Barcelona, Spain (J.A.-G., M.V.-B., A.F.-G., A.S.-P., J.C.); Department ESAII, EUETIB, Universidad Politécnica de Cataluña, Barcelona, Spain (P.G.); and Biochemistry and Molecular Biology Department, Hospital de la Santa Creu i Sant Pau, IIB-SantPau, Universidad Autónoma de Barcelona, Spain (J.O.-L.). jalvarezg@santpau.cat.
Miquel Vives-BorrásFrom Cardiology Department, Hospital de la Santa Creu i Sant Pau, IIB-SantPau, Universidad Autónoma de Barcelona, Spain (J.A.-G., M.V.-B., A.F.-G., A.S.-P., J.C.); Department ESAII, EUETIB, Universidad Politécnica de Cataluña, Barcelona, Spain (P.G.); and Biochemistry and Molecular Biology Department, Hospital de la Santa Creu i Sant Pau, IIB-SantPau, Universidad Autónoma de Barcelona, Spain (J.O.-L.).
Pedro GomisFrom Cardiology Department, Hospital de la Santa Creu i Sant Pau, IIB-SantPau, Universidad Autónoma de Barcelona, Spain (J.A.-G., M.V.-B., A.F.-G., A.S.-P., J.C.); Department ESAII, EUETIB, Universidad Politécnica de Cataluña, Barcelona, Spain (P.G.); and Biochemistry and Molecular Biology Department, Hospital de la Santa Creu i Sant Pau, IIB-SantPau, Universidad Autónoma de Barcelona, Spain (J.O.-L.).
Jordi Ordoñez-LlanosFrom Cardiology Department, Hospital de la Santa Creu i Sant Pau, IIB-SantPau, Universidad Autónoma de Barcelona, Spain (J.A.-G., M.V.-B., A.F.-G., A.S.-P., J.C.); Department ESAII, EUETIB, Universidad Politécnica de Cataluña, Barcelona, Spain (P.G.); and Biochemistry and Molecular Biology Department, Hospital de la Santa Creu i Sant Pau, IIB-SantPau, Universidad Autónoma de Barcelona, Spain (J.O.-L.).
Andreu Ferrero-GregoriFrom Cardiology Department, Hospital de la Santa Creu i Sant Pau, IIB-SantPau, Universidad Autónoma de Barcelona, Spain (J.A.-G., M.V.-B., A.F.-G., A.S.-P., J.C.); Department ESAII, EUETIB, Universidad Politécnica de Cataluña, Barcelona, Spain (P.G.); and Biochemistry and Molecular Biology Department, Hospital de la Santa Creu i Sant Pau, IIB-SantPau, Universidad Autónoma de Barcelona, Spain (J.O.-L.).
Antoni Serra-PeñarandaFrom Cardiology Department, Hospital de la Santa Creu i Sant Pau, IIB-SantPau, Universidad Autónoma de Barcelona, Spain (J.A.-G., M.V.-B., A.F.-G., A.S.-P., J.C.); Department ESAII, EUETIB, Universidad Politécnica de Cataluña, Barcelona, Spain (P.G.); and Biochemistry and Molecular Biology Department, Hospital de la Santa Creu i Sant Pau, IIB-SantPau, Universidad Autónoma de Barcelona, Spain (J.O.-L.).
Juan CincaFrom Cardiology Department, Hospital de la Santa Creu i Sant Pau, IIB-SantPau, Universidad Autónoma de Barcelona, Spain (J.A.-G., M.V.-B., A.F.-G., A.S.-P., J.C.); Department ESAII, EUETIB, Universidad Politécnica de Cataluña, Barcelona, Spain (P.G.); and Biochemistry and Molecular Biology Department, Hospital de la Santa Creu i Sant Pau, IIB-SantPau, Universidad Autónoma de Barcelona, Spain (J.O.-L.).
Hospital de Sant Pau · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe arrhythmogenesis of ventricular myocardial ischemia has been extensively studied, but models of atrial ischemia in humans are lacking. This study aimed at describing the electrophysiological alterations induced by acute atrial ischemia secondary to atrial coronary branch occlusion during elective coronary angioplasty. METHODS AND

resultsClinical data, 12-lead ECG, 12-hour Holter recordings, coronary angiography, and serial plasma levels of high-sensitivity troponin T and midregional proatrial natriuretic peptide were prospectively analyzed in 109 patients undergoing elective angioplasty of right or circumflex coronary arteries. Atrial coronary branches were identified and after the procedure patients were allocated into two groups: atrial branch occlusion (ABO, n=17) and atrial branch patency (non-ABO, n=92). In comparison with the non-ABO, patients with ABO showed: (1) higher incidence of periprocedural myocardial infarction (20% versus 53%, P=0.01); (2) more frequent intra-atrial conduction delay (19% versus 46%, P=0.03); (3) more marked PR segment deviation in the Holter recordings; and (4) higher incidence of atrial tachycardia (15% versus 41%, P=0.02) and atrial fibrillation (0% versus 12%, P=0.03). After adjustment by a propensity score, ABO was an independent predictor of periprocedural infarction (odds ratio, 3.4; 95% confidence interval, 1.01-11.6, P<0.05) and atrial arrhythmias (odds ratio, 5.1; 95% confidence interval, 1.2-20.5, P=0.02).

conclusionsSelective atrial coronary artery occlusion during elective percutaneous transluminal coronary angioplasty is associated with myocardial ischemic damage, atrial arrhythmias, and intra-atrial conduction delay. Our data suggest that atrial ischemic episodes might be considered as a potential cause of atrial fibrillation in patients with chronic coronary artery disease.

Indexed as

Coronary CirculationAction PotentialsAgedAngioplasty, Balloon, CoronaryArrhythmias, CardiacAtrial Natriuretic FactorBiomarkersChi-Square DistributionConstriction, PathologicCoronary AngiographyCoronary OcclusionCoronary VesselsElectrocardiography, AmbulatoryFemaleHeart AtriaHeart Conduction SystemAtrial Natriuretic FactorBiomarkersTroponin Tangioplasty, balloon, coronaryatrial fibrillationatrial standstillcoronary occlusionmyocardial infarctionPR segment deviation

Identifiers

PMID27151531
OpenAlexW2345345165

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.