Evidence map›Paper›PMID 27151303›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2017

Comparison of coronary flow reserve estimated by dynamic radionuclide SPECT and multi-detector x-ray CT.

Cecilia Marini, Sara Seitun, Camilla Zawaideh, Matteo Bauckneht, Margherita Castiglione Morelli, Pietro Ameri, Giulia Ferrarazzo, Irilda Budaj, Manrico Balbi, Francesco Fiz and 10 more

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Cardiac CT perfusion and FFRCardiovascular diagnosis and therapy · 2020
    Review
  2. Observational
  3. Review
  4. Myocardial perfusion with single-photon emission computed tomography, multidetector computed tomography, or neither?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017
    Article
  5. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors.

Cecilia MariniCNR Institute of Bioimaging and Molecular Physiology, Milan, Section of Genoa, Italy.
Sara SeitunInterventional Radiology, IRCCS-AOU San Martino-IST, Genoa, Italy.
Camilla ZawaidehClinic of Cardiovascular Diseases, IRCCS-AOU San Martino-IST, Genoa, Italy.
Matteo BaucknehtNuclear Medicine, IRCCS-AOU San Martino-IST, Genoa, Italy. bauckneht@yahoo.com.
Margherita Castiglione MorelliInterventional Radiology, IRCCS-AOU San Martino-IST, Genoa, Italy.
Pietro AmeriClinic of Cardiovascular Diseases, IRCCS-AOU San Martino-IST, Genoa, Italy.
Giulia FerrarazzoNuclear Medicine, IRCCS-AOU San Martino-IST, Genoa, Italy.
Irilda BudajInterventional Radiology, IRCCS-AOU San Martino-IST, Genoa, Italy.
Manrico BalbiClinic of Cardiovascular Diseases, IRCCS-AOU San Martino-IST, Genoa, Italy.
Francesco FizNuclear Medicine, IRCCS-AOU San Martino-IST, Genoa, Italy.
Sara BoccaliniInterventional Radiology, IRCCS-AOU San Martino-IST, Genoa, Italy.
Athena Galletto PregliascoInterventional Radiology, IRCCS-AOU San Martino-IST, Genoa, Italy.
Ambra BuschiazzoNuclear Medicine, IRCCS-AOU San Martino-IST, Genoa, Italy.
Alice SaraccoDITEN, University of Genoa, Genoa, Italy.
Maria Claudia BagnaraHealth Physics, IRCCS-AOU San Martino-IST, Genoa, Italy.
Paolo BruzziEpidemiology Unit, IRCCS-AOU San Martino-IST, Genoa, Italy.
Claudio BrunelliClinic of Cardiovascular Diseases, IRCCS-AOU San Martino-IST, Genoa, Italy.
Carlo FerroInterventional Radiology, IRCCS-AOU San Martino-IST, Genoa, Italy.
Gian Paolo BezanteClinic of Cardiovascular Diseases, IRCCS-AOU San Martino-IST, Genoa, Italy.
Gianmario SambucetiNuclear Medicine, IRCCS-AOU San Martino-IST, Genoa, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecent technical advances in multi-detector computed tomography (MDCT) allow for assessment of coronary flow reserve (CFR). We compared regional CFR by dynamic SPECT and by dynamic MDCT in patients with suspected or known coronary artery disease (CAD).

methodsThirty-five patients, (29 males, mean age 69 years) with greater than average Framingham risk of CAD, underwent dipyridamole vasodilator stress imaging. CFR was estimated using dynamic SPECT and dynamic MDCT imaging in the same patients. Myocardial perfusion findings were correlated with obstructive CAD (≥50% luminal narrowing) on CT coronary angiography (CA).

resultsMean CFR estimated by SPECT and MDCT in 595 myocardial segments was not different (1.51 ± 0.46 vs. 1.50 ± 0.37, p = NS). Correlation of segmental CFR by SPECT and MDCT was fair (r

conclusionDespite relative underestimation of high CFR values, MDCT CFR shows promise for assessing the pathophysiological significance of anatomic CAD.

Indexed as

Computed Tomography AngiographyFractional Flow Reserve, MyocardialMyocardial Perfusion ImagingTomography, Emission-Computed, Single-PhotonTomography, X-Ray ComputedAgedCoronary AngiographyCoronary Artery DiseaseCoronary CirculationDipyridamoleFemaleHumansMaleRiskDipyridamolecoronary artery diseaseCoronary flow reserveSPECTx-ray computed tomography

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.