Evidence map›Paper›PMID 27150801›Full record

ArticleCardiovascular and interventional radiology2016

Ga-68 DOTATOC PET/CT-Guided Biopsy and Cryoablation with Autoradiography of Biopsy Specimen for Treatment of Tumor-Induced Osteomalacia.

Majid Maybody, Ravinder K Grewal, John H Healey, Cristina R Antonescu, Louise Fanchon, Sinchun Hwang, Jorge A Carrasquillo, Assen Kirov, Azeez Farooki

Open access · greenAbstract readCase Reports
In one paragraph

Article in Cardiovascular and interventional radiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 26 citations in OpenAlex.

  1. A nomogram for predicting surgery outcome of tumor-induced osteomalacia: a case-control study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Article
  2. Article
  3. Article
  4. Treatment Advances in Tumor-Induced Osteomalacia.Calcified tissue international · 2025
    Review
  5. Article
  6. Review
  7. Advancements and Future Outlook of PET/CT-Guided Interventions.Techniques in vascular and interventional radiology · 2023
    Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Practice and prospects for PET/CT guided interventions.The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of... · 2021
    Review
  13. Review
  14. Diagnostic performance and impact on patient management ofEuropean journal of nuclear medicine and molecular imaging · 2018
    Article
  15. Multimodality Image-Guided Cryoablation for Inoperable Tumor-Induced Osteomalacia.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2017
    Article
  16. PET Molecular Imaging-Directed Biopsy: A Review.AJR. American journal of roentgenology · 2017
    Review
  17. Effective localization in tumor-induced osteomalacia usingEndocrinology, diabetes & metabolism case reports · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Majid MaybodyInterventional Radiology Service, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, M276C, New York, NY, 10065, USA. maybodym@mskcc.org.
Ravinder K GrewalMolecular Imaging and Therapy Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
John H HealeyOrthopedic Surgical Oncology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Cristina R AntonescuDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Louise FanchonDepartment of Physics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Sinchun HwangDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Jorge A CarrasquilloMolecular Imaging and Therapy Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Assen KirovDepartment of Physics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Azeez FarookiDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Memorial Sloan Kettering Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome caused by small benign tumors of mesenchymal origin also known as phosphaturic mesenchymal tumors mixed connective tissue variant. Excellent prognosis is expected with eradication of the culprit tumor. These small tumors are notoriously difficult to localize with conventional imaging studies; this often leads to an extensive work up and prolonged morbidity. We report a patient with clinical diagnosis of TIO whose culprit tumor was localized with Ga-68 DOTATOC PET/CT and MRI. Biopsy and cryoablation were performed under Ga-68 DOTATOC PET/CT guidance. Autoradiography of the biopsy specimen was performed and showed in situ correlation between Ga-68 DOTATOC uptake and histopathology with millimeter resolution.

Indexed as

AutoradiographyCryosurgeryFemaleGallium RadioisotopesHumansImage-Guided BiopsyMiddle AgedNeoplasms, Connective TissueOctreotideOsteomalaciaParaneoplastic SyndromesPositron Emission Tomography Computed TomographyRadiopharmaceuticalsTreatment OutcomeEdotreotideGallium RadioisotopesOctreotideRadiopharmaceuticalsCryoablationDOTATOC PET/CTOsteomalaciaTumor-induced

Identifiers

PMID27150801
PMCPMC5483397
OpenAlexW2464941960

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.