Evidence map›Paper›PMID 27149552›Full record

ArticleNeuropsychology2016

Factors related to racial differences in late-life level of cognitive function.

Robert S Wilson, Kumar B Rajan, Lisa L Barnes, Jennifer Weuve, Denis A Evans

Abstract read
In one paragraph

Article in Neuropsychology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Measuring Cognitive Health in Ethnically Diverse Older Adults.The journals of gerontology. Series B, Psychological sciences and social sciences · 2022
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Education Differentially Buffers Cognitive Performance in Black and White Older Adults.The journals of gerontology. Series B, Psychological sciences and social sciences · 2019
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Robert S WilsonRush Alzheimer's Disease Center, Department of Neurological Sciences, Rush University Medical Center.
Kumar B RajanRush Institute for Healthy Aging.
Lisa L BarnesRush Alzheimer's Disease Center, Department of Neurological Sciences, Rush University Medical Center.
Jennifer WeuveRush Institute for Healthy Aging.
Denis A EvansRush Institute for Healthy Aging.

Funding

SUPPLEMENT TO RUSH ALZHEIMERS DISEASE CENTER COREP30AG010161 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BENNETT, DAVID ALAN · 1991 to 2020
$49.1M
Risk Factors for Incident Alzheimer's Disease in a Biracial CommunityR01AG011101 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI EVANS, DENIS A · 1993 to 2010
$24.7M
Risk Factors for Cognitive Decline in African-AmericansR01AG022018 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BARNES, LISA L · 2004 to 2025
$18.2M
NIA NIH HHS P30 AG010161NIA NIH HHS R01 AG011101NIA NIH HHS R01 AG022018
6 · The paper itself

Abstract

objectiveThe study aim was to identify factors associated with racial differences in level of cognitive function in old age.

methodOlder Black (n = 5,950) and White (n = 3,469) residents of a geographically defined urban community were randomly split into exploratory and confirmatory subgroups. A global measure of cognition was derived from 4 brief performance tests, and potential correlates of cognition (candidates) were selected from demographic, health-related, and experiential measures. In the exploratory subgroup, using a stepwise search algorithm, we examined the cognitive difference by race and then allowed candidate measures and Race × Candidate Measure interactions to enter the model.

resultsThe cognitive score in the exploratory subgroup (M = 0.257, SD = 0.714) was a mean of 0.403 unit lower in Black persons than White persons (SE = 0.021, p < .001), and race accounted for 7% of cognitive variability. After the candidate selection process, 16 measures were retained, including 12 candidate measures and the 2-way interactions of race with education, age, reading/cognitive activity, and neuroticism. In this model, which accounted for 45% of the variability in global cognition, race was no longer associated with global cognition (coefficient = 0.012, SE = 0.110, p = .912). Findings were replicated in the confirmatory subgroup.

conclusionThese cross-sectional analyses suggest that consideration of demographic, health-related, and experiential factors greatly attenuates racial differences in late-life level of cognition. (PsycINFO Database Record

Indexed as

ReadingAgedAged, 80 and overAgingAnxiety DisordersBlack or African AmericanChicagoCognitionCross-Sectional StudiesFemaleHumansMaleMiddle AgedNeuroticismWhite People

Identifiers

PMID27149552
PMCPMC4948284

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.