ArticleMedicine2016
The Explorative Analysis to Revise Fear Network Model for Panic Disorder: Functional Connectome Statistics.
Article in Medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Gray Matter Alterations in Panic Disorder: A Voxel-Wise Meta-Analysis.Psychiatry and clinical psychopharmacology · 2023Pooled it
- Involvement of Adenosine ABrain and behavior · 2026Article
- Enhanced interhemispheric resting-state functional connectivity of the visual network is an early treatment response of paroxetine in patients with panic disorder.European archives of psychiatry and clinical neuroscience · 2024Article
- Internalizing Symptoms and Adverse Childhood Experiences Associated With Functional Connectivity in a Middle Childhood Sample.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2024Article
- Breaking the Fear Barrier: Aberrant Activity of Fear Networks as a Prognostic Biomarker in Patients with Panic Disorder Normalized by Pharmacotherapy.Biomedicines · 2023Article
- Altered White Matter Network Topology in Panic Disorder.Journal of personalized medicine · 2023Article
- ADORA2A variation and adenosine ATranslational psychiatry · 2020Article
- Fear Network Model in Panic Disorder: The Past and the Future.Psychiatry investigation · 2019Article
- Decreased temporal variabilities of functional connectivities in insula and lingual gyrus are associated with better early treatment response in patients with panic disorder.Journal of psychiatry & neuroscience : JPNArticle
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Functional connectome analysis in panic disorder (PDO) is a relatively new field for research. We tried to investigate the functional connectome alterations in PDO to re-examine the precision and role of fear network model for the pathophysiology of PDO.We enrolled 53 PDO patients and 54 controls with imaging data in this study. After preprocessing, we calculated the connectivity matrix of functional connectivity in whole brain for each subject. Then network-based statistics (The University of Melbourne and Melbourne Health, Australia) of connectome was used to perform group comparisons between patients and controls. The correlation between network measures of significant subnetwork and illness duration or severity of PDO was also performed.Within the 6 network models, only 1 network survived after multiple corrections. We found decreased functional connectivity in the edges between the following nodes: the left parahippocampal gyrus, bilateral precentral gyri, bilateral middle cingulate gyri, bilateral supramarginal gyri, bilateral calcarine fissures, and right lingual gyrus. The central hubs were the left parahippocampal gyrus and left precentral gyrus. The importance of limbic areas and connection with sensory and motor regions might shed light on the revision of fear network model for the pathophysiology of PDO.
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