Evidence map›Paper›PMID 27149477›Full record

ArticleMedicine2016

Association Between Serum Levels of Vitamin D and the Risk of Post-Stroke Anxiety.

Chaowen Wu, Wenwei Ren, Jianhua Cheng, Beilei Zhu, Qianqian Jin, Liping Wang, Cao Chen, Lin Zhu, Yaling Chang, Yingying Gu and 5 more

Open access · goldAbstract read
In one paragraph

Article in Medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Sleep Disturbances in Generalized Anxiety Disorder: The Role of Calcium Homeostasis Imbalance.International journal of environmental research and public health · 2023
    Article
  4. Vitamin D3 and Ischemic Stroke: A Narrative Review.Antioxidants (Basel, Switzerland) · 2022
    Review
  5. Article
  6. Nutrition as Metabolic Treatment for Anxiety.Frontiers in psychiatry · 2021
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Non-cardiac Chest Pain and Anxiety: A Possible Link to Vitamin D and Calcium.Journal of clinical psychology in medical settings · 2019
    Observational
  12. Levels of 25-hydroxyvitamin DMetabolic brain disease · 2019
    Article
  13. Article
  14. Article
  15. Article
  16. Role of Vitamin D in the Outcome of Ischemic Stroke- A Randomized Controlled Trial.Journal of clinical and diagnostic research : JCDR · 2017
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Chaowen WuFrom the Department of Neurology (CW, WR, JC, BZ, QJ, LW, CC, LZ, YC, YG, JZ, DL, BS, JH), The First Affiliated Hospital of Wenzhou Medical University and Department of Neurology, Ruian People's Hospital, Wenzhou (SZ), People's Republic of China.
Wenwei Ren
Jianhua Cheng
Beilei Zhu
Qianqian Jin
Liping Wang
Cao Chen
Lin Zhu
Yaling Chang
Yingying Gu
Jiyun Zhao
Dezhao Lv
Bei Shao
Shunkai Zhang
Jincai He
Wenzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Low levels of serum vitamin D are common in patients with mood disorders and stroke. It has been shown that low levels of serum vitamin D indicate a risk of depression in post-stroke subjects. Our aim was to determine the relationship between vitamin D and post-stroke anxiety (PSA).A consecutive series of 226 first acute ischemic stroke patients were recruited and followed up for 1 month. Serum levels of vitamin D were measured within 24 hours of admission. Patients with significant clinical symptoms of anxiety and a Hamilton anxiety scale score >7 were diagnosed as having PSA. In addition, 100 healthy subjects were recruited as controls and underwent measurements of serum vitamin D.A total of 60 patients (26.55%) showed anxiety at 1 month. Both PSA patients and non-PSA patients had lower serum levels of vitamin D than healthy subjects. A significant relationship was found between PSA and serum levels of vitamin D. Low serum levels of vitamin D (≤38.48 nmol/L) were independently associated with the development of PSA (OR: 2.49, 95% CI: 1.21-5.13, P = 0.01).Serum vitamin D status is related to the occurrence of anxiety in post-stroke patients and may be an independent risk factor of PSA after 1 month.

Indexed as

AnxietyFemaleHumansLogistic ModelsMaleMiddle AgedPsychiatric Status Rating ScalesStatistics, NonparametricStrokeVitamin DVitamin D DeficiencyVitaminsVitamin DVitamins

Identifiers

PMID27149477
PMCPMC4863794
OpenAlexW2346492119

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.