Evidence map›Paper›PMID 27149232›Full record

ArticleANS. Advances in nursing science

Mechanisms of the Maternal Exposome and Implications for Health Outcomes.

Michelle L Wright, Angela R Starkweather, Timothy P York

Abstract read
In one paragraph

Article in ANS. Advances in nursing science. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Genomic Impacts of Biological Exposures.Journal of developmental biology · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Geospatial Science for the Environmental Epidemiology of Cancer in the Exposome Era.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024
    Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Michelle L WrightUniversity of Connecticut, School of Nursing, Storrs, Connecticut (Dr Starkweather), Yale University, School of Nursing, West Haven, Connecticut (Dr Wright); and Virginia Institute for Psychiatric and Behavioral Genetics, Department of Human and Molecular Genetics, and Department of Obstetrics and Gynecology, Virginia Commonwealth University School of Medicine, Richmond (Dr York).
Angela R Starkweather
Timothy P York

Funding

VCU NIMHD Comprehensive Center of Excellence (Project 1; PI: Strauss)P60MD002256 · NIMHD · VIRGINIA COMMONWEALTH UNIVERSITY · PI BRADLEY, CATHY J · 2007 to 2016
$13.1M
Epigenetics and Psychoneurologic Symptoms in Women with Breast CancerR01NR012667 · NINR · VIRGINIA COMMONWEALTH UNIVERSITY · PI JACKSON-COOK, COLLEEN K, LYON, DEBRA E · 2010 to 2014
$3.1M
Pathways to Alcohol Use Disorders in ALSPAC: A Genetic-Developmental StudyR01AA018333 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI DICK, DANIELLE M, KENDLER, KENNETH SEEDMAN · 2010 to 2014
$2.8M
Pain Sensitivity in Low Back PainR01NR013932 · NINR · VIRGINIA COMMONWEALTH UNIVERSITY · PI STARKWEATHER, ANGELA RENEE · 2013 to 2015
$1.3M
Epigenetic, Telomere & Chromosome Changes in Adult Twins Having Child AdversityR01AG037986 · NIA · VIRGINIA COMMONWEALTH UNIVERSITY · PI JACKSON-COOK, COLLEEN K, YORK, TIMOTHY P · 2010 to 2014
$472k
NIAAA NIH HHS R01 AA018333NIA NIH HHS R01 AG037986NIMHD NIH HHS P60 MD002256NINR NIH HHS R01 NR012667NINR NIH HHS R01 NR013932
6 · The paper itself

Abstract

It is well established that the environment contributes to health. However, few studies have evaluated environmental exposures in women that may influence future health of their offspring. Knowledge gained may inform nursing how to better advocate for patients and families, and provide individualized interventions and education. Therefore, a more comprehensive investigation of the maternal exposome to uncover mechanistic insight into complex disease in offspring is warranted. To advance understanding of biologic mechanisms that contribute to high-risk birth outcomes and offspring predisposition to disease, it will be necessary to measure a range of exposures and biomarkers before and during pregnancy.

Indexed as

Epigenesis, GeneticGene Expression Regulation, DevelopmentalAdultBiomarkersFemaleFetal DevelopmentHumansMaternal ExposurePregnancyYoung AdultBiomarkers

Identifiers

PMID27149232
PMCPMC4860277

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.