ArticleJournal of palliative medicine2016
Association between Daytime Activity, Fatigue, Sleep, Anxiety, Depression, and Symptom Burden in Advanced Cancer Patients: A Preliminary Report.
Article in Journal of palliative medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00424099 (A Randomized Controlled Trial of Methylphenidate and a Nursing Telephone Intervention), which is not on this map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Randomized Controlled Trial of Methylphenidate and a Nursing Telephone Intervention (NTI) for Fatigue in Advanced Cancer Patients
Who cites it
22 citing papers in PubMed.
- The short-term impact of methylprednisolone on patient-reported sleep in patients with advanced cancer in a randomized, placebo-controlled, double-blind trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Trial
- Prevalence and Correlates of Sleep Difficulties in a Large Multicenter Outpatient Oncology Population as Identified through Practice-Based Screening.Cancer research communications · 2026Article
- Sleep trajectory of hospitalized medically ill older adults: do sleep medications make a difference?Sleep · 2025Article
- Sleep quality, anxiety, and depression in palliative care patients.Palliative & supportive care · 2025Article
- Association between malnutrition and anxiety in cancer patients-a retrospective study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- Integrative Oncology Approaches to Reduce Recurrence of Disease and Improve Survival.Current oncology reports · 2024Review
- A network approach to understanding occupational psychological distress: linking depression, anxiety, and burnout among Chinese healthcare professionals.Frontiers in psychology · 2024Article
- Psychological assessment and the role of the psychologist in early palliative care.Frontiers in psychology · 2024Article
- Relationship of sleep-quality and social-anxiety in patients with breast cancer: a network analysis.BMC psychiatry · 2023Article
- Cancer-related fatigue and depression: a monocentric, prospective, cross-sectional study in advanced solid tumors.ESMO open · 2022Article
- Hypnosis and cognitive behavioral therapy with online sessions to reduce fatigue in patients undergoing chemotherapy for a metastatic colorectal cancer: Rational and study protocol for a feasibility study.Frontiers in psychology · 2022Article
- Anamorelin combined with physical activity, and nutritional counseling for cancer-related fatigue: a preliminary study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Article
- Contribution of Sleep Disruption and Sedentary Behavior to Fatigue in Survivors of Allogeneic Hematopoietic Cell Transplant.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2021Article
- Evaluation and Management of Sleep and Circadian Rhythm Disturbance in Cancer.Current treatment options in oncology · 2021Review
- Brief Report: Hispanic Patients' Trajectory of Cancer Symptom Burden, Depression, Anxiety, and Quality of Life.Nursing reports (Pavia, Italy) · 2021Article
- Patient characteristics associated with sleep disturbance in breast cancer survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Article
- Brain-derived neurotrophic factor polymorphism Val66Met protects against cancer-related fatigue.Translational psychiatry · 2020Article
- Sleep quality in hospitalized patients with advanced cancer: an observational study using self-reports of sleep and actigraphy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020Observational
- Salivary Cortisol Profile Under Different Stressful Situations in Female College Students: Moderating Role of Anxiety and Sleep.The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses · 2018Article
- Circadian rest-activity rhythm as an objective biomarker of patient-reported outcomes in patients with advanced cancer.Cancer medicine · 2018Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
backgroundThere is limited research in advanced cancer patients (ACP) regarding association between objectively measured daytime activity and sleep (as measured by actigraphy), patient characteristics, and cancer symptoms (fatigue, sleep, anxiety, depression, cachexia, and symptom distress scores [SDSs]).
objectivesOur aim of the study was to determine the association between mean daytime activity (MDTA) and the following items: fatigue (FACIT-F), SDSs (Edmonton Symptom Assessment Scale [ESAS]), sleep quality (Pittsburg Sleep Quality Index [PSQI]), objective sleep variables (OSV) (sleep onset, sleep efficacy, wake after sleep onset, total sleep time), anxiety and depression (Hospital Anxiety and Depression Scale [HADS]), body composition scores, and overall survival (OS). We also examined the association between sleep [PSQI and OSV scores] and FACIT-F, HADS, and ESAS.
methodsSecondary analysis of a recent clinical trial of cancer-related fatigue in advanced cancer (NCT00424099). Association between MDTA and OSV (measured by actigraphy) during the first week of the study and patient characteristics, symptoms (FACIT-F, ESAS, HADS, and PSQI), and OS were analyzed.
resultsSeventy-nine eligible patients were evaluable. The median age was 57 years. Median MDTA was 248.43 counts/minute. Multivariate analysis shows that low MDTA was significantly associated with age, gender, Functional Assessment of Cancer Therapy (FACT)-Functional Well-Being (FWB), ESAS dyspnea, HADS-anxiety, and total sleep time. MDTA was not associated with FACIT-F (p = 0.997) and OS (p = 0.18). Sleep quality (PSQI) was significantly associated with FACIT-F, HADS, ESAS anxiety, and depression, but none of these variables was associated with OSV.
conclusionIn ACP, lower MDTA was significantly associated with age, gender, FACT-FWB, ESAS dyspnea, HADS-anxiety, and total sleep time. Both sleep quality and cancer-related fatigue scores were strongly associated with depression and anxiety. More research is needed.
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