ArticleBio-protocol2013
Rat Model of Chronic Midthoracic Lateral Hemisection.
Article in Bio-protocol, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Authors and funding
1 author.
Funding
Abstract
Although most spinal cord injuries (SCI) are anatomically incomplete, only limited functional recovery has been observed in people and rats with partial lesions. To address why surviving fibers cannot mediate more complete recovery, it is important to evaluate the physiological and anatomical status of spared fibers. These experiments require use of animal models. Here we describe a midthoracic unilateral spinal cord hemisection (HX; corresponds to Brown-Sequard lesion in humans) in adult rats. This is a useful animal model for partial injuries because there is a clear lesion of one entire side of the cord with intact fibers remaining on the contralateral side. This model allows the study and comparison of how acute and chronic trauma affect function of the surviving fibers.
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Registered trials
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