ReviewFrontiers in plant science2016
Cenh3: An Emerging Player in Haploid Induction Technology.
Review in Frontiers in plant science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed, 91 citations in OpenAlex.
- Genome-wide profiling and functional study of short N-terminal H2B variants in Arabidopsis.Journal of advanced research · 2025Article
- Direct haploid formation in Arabidopsis using transgenic CENH3-based inducers.Plant cell reports · 2025Article
- Recent Progress on Plant Apomixis for Genetic Improvement.International journal of molecular sciences · 2024Review
- Haploid identification in maize.Frontiers in plant science · 2024Review
- Efficient multi-allelic genome editing via CRISPR-Cas9 ribonucleoprotein-based delivery toFrontiers in plant science · 2024Article
- Haploid induction: an overview of parental factor manipulation during seed formation.Frontiers in plant science · 2024Review
- Plasticity of parental CENH3 incorporation into the centromeres in wheat × barley F1 hybrids.Frontiers in plant science · 2024Article
- Embryo Rescue in Plant Breeding.Plants (Basel, Switzerland) · 2023Review
- High temperature increases centromere-mediated genome elimination frequency and enhances haploid induction in Arabidopsis.Plant communications · 2023Article
- Accelerated Breeding forPlants (Basel, Switzerland) · 2023Review
- The Roads to Haploid Embryogenesis.Plants (Basel, Switzerland) · 2023Review
- Recurrent Plant-Specific Duplications of KNL2 and Its Conserved Function as a Kinetochore Assembly Factor.Molecular biology and evolution · 2022Article
- Omics Path to Increasing Productivity in Less-Studied Crops Under Changing Climate-Lentil a Case Study.Frontiers in plant science · 2022Review
- Overexpression of ModifiedFrontiers in plant science · 2022Article
- Maternal karyogene and cytoplasmic genotype affect the induction efficiency of doubled haploid inducer in Brassica napus.BMC plant biology · 2021Article
- Haploid induction and its application in maize breeding.Molecular breeding : new strategies in plant improvement · 2021Article
- Chromosome doubling methods in doubled haploid and haploid inducer-mediated genome-editing systems in major crops.Plant cell reports · 2021Review
- Overview of In Vitro and In Vivo Doubled Haploid Technologies.Methods in molecular biology (Clifton, N.J.) · 2021Review
- Haploid induction by a maizeScience advances · 2021Article
- Only the Rye Derived Part of the 1BL/1RS Hybrid Centromere Incorporates CENH3 of Wheat.Frontiers in plant science · 2021Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
True-breeding lines are required for the development and production of crop varieties. In a classical breeding approach these lines are obtained through inbreeding, and often 7-9 generations of inbreeding is performed to achieve the desired level of homozygosity, over a period of several years. In contrast, the chromosomes of haploids can be doubled to produce true-breeding lines in a single generation. Over the last century, scientists have developed a variety of techniques to induce haploids and doubled haploids, though these techniques apply only to particular crop varieties. Ravi and Chan (2010) discovered that haploids could be obtained in Arabidopsis through the manipulation of the centromere-specific histone 3 variant, CENH3. Their approach, which involved extensive modifications to a transgenic CENH3, held promise of being translated to crop species, and has been successfully employed in maize (see Kelliher et al., 2016). Refinements of this technology have since been developed which indicate that non-transgenic modifications to CENH3 will also induce haploids. The complementation of a cenh3 null by CENH3 from closely related plant species can result in plants that are fertile but haploid-inducing on crossing by CENH3 wt plants- suggesting that introgression of alien CENH3 may produce non-transgenic haploid inducers. Similarly, a remarkably wide variety of point mutations in CENH3, inducible by chemical agents, have recently been shown to result in haploid induction on crossing by wild-type CENH3 plants. These CENH3-variant plants grow normally, are fully fertile on self-pollination, and may be present in existing mutagenized collections.
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