Evidence map›Paper›PMID 27148272›Full record

ReviewFrontiers in immunology2016

The Contribution of Immune Evasive Mechanisms to Parasite Persistence in Visceral Leishmaniasis.

Elisangela Oliveira de Freitas, Fabiana Maria de Souza Leoratti, Célio Geraldo Freire-de-Lima, Alexandre Morrot, Daniel Ferreira Feijó

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 68 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Interleukin-27 Functional Duality BalancesFrontiers in immunology · 2020
    Review
  15. Article
  16. Article
  17. Frontiers in cellular and infection microbiology · 2019
    Review
  18. Article
  19. Antileishmanial activity and immunomodulatory effect ofThe journal of venomous animals and toxins including tropical diseases · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Elisangela Oliveira de FreitasThe Jenner Institute, University of Oxford , Oxford , UK.
Fabiana Maria de Souza LeorattiThe Jenner Institute, University of Oxford , Oxford , UK.
Célio Geraldo Freire-de-LimaInstituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro , Rio de Janeiro , Brazil.
Alexandre MorrotLaboratorio de Biologia do Sistema Imune, Departmento de Imunologia, Instituto de Microbiologia, Universidade Federal do Rio de Janeiro , Rio de Janeiro , Brazil.
Daniel Ferreira FeijóLaboratório Integrado de Microbiologia e Imunoregulação, Centro de Pesquisas Gonçalo Moniz, Fundação Oswaldo Cruz (FIOCRUZ) , Salvador , Brazil.
Jenner Institute · GBUniversidade Federal do Rio de Janeiro · BRFundação Oswaldo Cruz · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leishmania is a genus of protozoan parasites that give rise to a range of diseases called Leishmaniasis that affects annually an estimated 1.3 million people from 88 countries. Leishmania donovani and Leishmania (L.) infantum chagasi are responsible to cause the visceral leishmaniasis. The parasite can use assorted strategies to interfere with the host homeostasis to establish persistent infections that without treatment can be lethal. In this review, we highlight the mechanisms involved in the parasite subversion of the host protective immune response and how alterations of host tissue physiology and vascular remodeling during VL could affect the organ-specific immunity against Leishmania parasites.

Indexed as

host protective responsesimmune evasive mechanismsLeishmania donovanileishmaniasistreatment

Identifiers

PMID27148272
PMCPMC4840207
OpenAlexW2339970694

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.