Evidence map›Paper›PMID 27147957›Full record

ReviewFrontiers in neuroscience2016

Chemicals, Nutrition, and Autism Spectrum Disorder: A Mini-Review.

Takeo Fujiwara, Naho Morisaki, Yukiko Honda, Makiko Sampei, Yukako Tani

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
9.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 98 citations in OpenAlex.

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  19. Effect of environmental toxicants on neuronal functions.Environmental science and pollution research international · 2020
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Takeo FujiwaraDepartment of Social Medicine, National Research Institute for Child Health and Development, Okura, Setagaya-ku, Tokyo, Japan; Department of Global Health Promotion, Tokyo Medical and Dental UniversityTokyo, Japan.
Naho MorisakiDepartment of Social Medicine, National Research Institute for Child Health and Development , Okura, Setagaya-ku, Tokyo, Japan.
Yukiko HondaDepartment of Social Medicine, National Research Institute for Child Health and Development, Okura, Setagaya-ku, Tokyo, Japan; Global Cooperation Institute for Sustainable Cities, Yokohama City UniversityYokohama, Japan.
Makiko SampeiDepartment of Social Medicine, National Research Institute for Child Health and Development , Okura, Setagaya-ku, Tokyo, Japan.
Yukako TaniDepartment of Social Medicine, National Research Institute for Child Health and Development, Okura, Setagaya-ku, Tokyo, Japan; Department of Global Health Promotion, Tokyo Medical and Dental UniversityTokyo, Japan; Department of Health Education and Health Sociology, School of Public Health, The University of TokyoTokyo, Japan.
National Center For Child Health and Development · JPTokyo Medical and Dental University · JPUniversity of Tokyo Health Sciences · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rapid increase of the prevalence of autism spectrum disorder (ASD) suggests that exposure to chemicals may impact the development of ASD. Therefore, we reviewed literature on the following chemicals, nutrient to investigate their association with ASD: (1) smoke/tobacco, (2) alcohol, (3) air pollution, (4) pesticides, (5) endocrine-disrupting chemicals, (6) heavy metals, (7) micronutrients, (8) fatty acid, and (9) parental obesity as a proxy of accumulation of specific chemicals or nutritional status. Several chemical exposures such as air pollution (e.g., particular matter 2.5), pesticides, bisphenol A, phthalates, mercury, and nutrition deficiency such as folic acid, vitamin D, or fatty acid may possibly be associated with an increased risk of ASD, whereas other traditional risk factors such as smoking/tobacco, alcohol, or polychlorinated biphenyls are less likely to be associated with ASD. Further research is needed to accumulate evidence on the association between chemical exposure and nutrient deficiencies and ASD in various doses and populations.

Indexed as

air pollutionautism spectrum disorderchemicalsenvironmentfatty acidheavy metalmicronutrientspesticide

Identifiers

PMID27147957
PMCPMC4837386
OpenAlexW2339579913

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.