ReviewFrontiers in neuroscience2016
Value and Efficacy of Transcranial Direct Current Stimulation in the Cognitive Rehabilitation: A Critical Review Since 2000.
Review in Frontiers in neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 3 syntheses or guidelines pooled it, 90 citations in OpenAlex.
- Digitalized transcranial electrical stimulation: A consensus statement.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2022Pooled it
- Effects of Transcranial Direct Current Stimulation (tDCS) on Cognitive Performance and Cerebral Oxygen Hemodynamics: A Systematic Review.Frontiers in human neuroscience · 2021Pooled it
- Transcranial Direct Current Stimulation (tDCS) as a Useful Rehabilitation Strategy to Improve Cognition in Patients With Alzheimer's Disease and Parkinson's Disease: An Updated Systematic Review of Randomized Controlled Trials.Frontiers in neurology · 2021Pooled it
- Research on the Effect of MT+FES Training on Sensorimotor Cortex.Neural plasticity · 2022Trial
- Effect of transcranial direct current stimulation combined with cognitive training on cognitive functioning in older adults with HIV: A pilot study.Applied neuropsychology. AdultTrial
- Layers of the monkey visual cortex are selectively modulated during electrical stimulation.PLoS biology · 2025Article
- Neural Mechanisms Underlying Robust Target Selection in Response to Microstimulation of the Oculomotor System.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Protocol for a randomized controlled trial: efficacy and mechanisms of dual-target anodal tDCS in post-stroke cognitive impairment.Frontiers in human neuroscience · 2025Article
- Article
- Transcranial Direct Current Stimulation to Ameliorate Post-Stroke Cognitive Impairment.Brain sciences · 2024Review
- An Educational Program for Remote Training and Supervision of Home-Based Transcranial Electrical Stimulation: Feasibility and Preliminary Effectiveness.Neuromodulation : journal of the International Neuromodulation Society · 2024Article
- Perspectives on Optimized Transcranial Electrical Stimulation Based on Spatial Electric Field Modeling in Humans.Journal of clinical medicine · 2024Review
- Tracking the current in the Alzheimer's brain - Systematic differences between patients and healthy controls in the electric field induced by tDCS.Neuroimage. Reports · 2023Article
- Inconsistencies in mapping current distribution in transcranial direct current stimulation.Frontiers in neuroimaging · 2022Article
- Optimized Magnetic Stimulation Induced Hypoconnectivity Within the Executive Control Network Yields Cognition Improvements in Alzheimer's Patients.Frontiers in aging neuroscience · 2022Article
- Prospective memory impairment in neurological disorders: implications and management.Nature reviews. Neurology · 2021Review
- Customized Application of tDCS for Clinical Rehabilitation in Alzheimer's Disease.Frontiers in human neuroscience · 2021Article
- Can accelerated transcranial direct current stimulation improve memory functions? An experimental, placebo-controlled study.Heliyon · 2020Article
- Sleep, Noninvasive Brain Stimulation, and the Aging Brain: Challenges and Opportunities.Ageing research reviews · 2020Review
- Individually customized transcranial temporal interference stimulation for focused modulation of deep brain structures: a simulation study with different head models.Scientific reports · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Non-invasive brain stimulation techniques, including transcranial direct current stimulation (t-DCS) have been used in the rehabilitation of cognitive function in a spectrum of neurological disorders. The present review outlines methodological communalities and differences of t-DCS procedures in neurocognitive rehabilitation. We consider the efficacy of tDCS for the management of specific cognitive deficits in four main neurological disorders by providing a critical analysis of recent studies that have used t-DCS to improve cognition in patients with Parkinson's Disease, Alzheimer's Disease, Hemi-spatial Neglect, and Aphasia. The evidence from this innovative approach to cognitive rehabilitation suggests that tDCS can influence cognition. However, the results show a high variability between studies both in terms of the methodological approach adopted and the cognitive functions targeted. The review also focuses both on methodological issues such as technical aspects of the stimulation (electrode position and dimension; current intensity; duration of protocol) and on the inclusion of appropriate assessment tools for cognition. A further aspect considered is the optimal timing for administration of tDCS: before, during or after cognitive rehabilitation. We conclude that more studies using common methodology are needed to gain a better understanding of the efficacy of tDCS as a new tool for rehabilitation of cognitive disorders in a range of neurological disorders.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.