Evidence map›Paper›PMID 27147723›Full record

ArticleJournal of clinical microbiology2016

Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry Fails To Identify Nontuberculous Mycobacteria from Primary Cultures of Respiratory Samples.

Kim van Eck, Dirk Faro, Melanie Wattenberg, Arjan de Jong, Saskia Kuipers, Jakko van Ingen

Abstract readEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Treatment of Nontuberculous Mycobacterial Pulmonary Disease: An Official ATS/ERS/ESCMID/IDSA Clinical Practice Guideline.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020
    Guideline
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  6. Review
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  11. Review of the impact of MALDI-TOF MS in public health and hospital hygiene, 2018.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2019
    Article
  12. Rapid Identification of Clinically RelevantJournal of clinical microbiology · 2019
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kim van EckDepartment of Medical Microbiology, Radboud University Medical Center, Nijmegen, the Netherlands.
Dirk FaroDepartment of Medical Microbiology, Radboud University Medical Center, Nijmegen, the Netherlands.
Melanie WattenbergDepartment of Medical Microbiology, Radboud University Medical Center, Nijmegen, the Netherlands.
Arjan de JongDepartment of Medical Microbiology, Radboud University Medical Center, Nijmegen, the Netherlands.
Saskia KuipersDepartment of Medical Microbiology, Radboud University Medical Center, Nijmegen, the Netherlands.
Jakko van IngenDepartment of Medical Microbiology, Radboud University Medical Center, Nijmegen, the Netherlands Jakko.vanIngen@radboudumc.nl.ORCID http://orcid.org/0000-0002-0581-2003

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have assessed matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) identification (Bruker) of nontuberculous mycobacteria from newly positive liquid cultures of respiratory samples. Twelve (22%) of 54 isolates were identified directly from liquid medium. After subculture and with manual laser operation, this rose to 49/54 isolates (91%). MALDI-TOF MS is less promising than previously suggested.

Indexed as

Bacteriological TechniquesHumansMycobacterium Infections, NontuberculousNontuberculous MycobacteriaSensitivity and SpecificitySpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationSputum

Identifiers

PMID27147723
PMCPMC4922120

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.