Evidence map›Paper›PMID 27147714›Full record

ArticleJournal of the Pediatric Infectious Diseases Society2016

First Report of a Verona Integron-Encoded Metallo-β-Lactamase-Producing Klebsiella pneumoniae Infection in a Child in the United States.

Pranita D Tamma, Nuntra Suwantarat, Susan D Rudin, Latania K Logan, Patricia J Simner, Laura J Rojas, Maria F Mojica, Karen C Carroll, Robert A Bonomo

Open access · bronzeAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the Pediatric Infectious Diseases Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Treatment of Carbapenem-Resistant Enterobacteriaceae Infections in Children.Journal of the Pediatric Infectious Diseases Society · 2020
    Review
  3. The rapid spread of carbapenem-resistant Enterobacteriaceae.Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy · 2016
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Pranita D TammaDivisions of Pediatric Infectious Diseases.
Nuntra SuwantaratMedical Microbiology, Johns Hopkins University School of Medicine, Baltimore, Maryland Chulabhorn International College of Medicine, Thammasat University, Pathumthani, Thailand.
Susan D RudinResearch Service.
Latania K LoganSection of Pediatric Infectious Diseases, Department of Pediatrics, Rush University Medical Center, Rush Medical College, Chicago, Illinois Louis Stokes Cleveland Department of Veterans Affairs Medical Center.
Patricia J SimnerMedical Microbiology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Laura J RojasResearch Service Department of Medicine Department of Molecular Biology and Microbiology.
Maria F MojicaResearch Service Department of Medicine Department of Biochemistry.
Karen C CarrollMedical Microbiology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Robert A BonomoGeriatrics Research, Education and Clinical Center, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Ohio Department of Medicine Department of Molecular Biology and Microbiology Department of Biochemistry Department of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, Ohio.
Johns Hopkins University · USLouis Stokes Cleveland VA Medical Center · USPediatric Infectious Diseases Society · USRush University Medical Center · USThammasat University · TH

Funding

Understanding B-Lactam Resistance in Acinetobacter baumanniiR01AI072219 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI ROBERT A. BONOMO, Philip N. Rather · 2007 to 2026
$6.6M
Understanding ceftazidime resistance in SHV B-LactamasesR01AI063517 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI BONOMO, ROBERT A. · 2005 to 2023
$4.9M
A Mechanism-Based Approach to Metallo-beta-Lactamase InhibitionR01AI100560 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI BONOMO, ROBERT A., SPENCER, JAMES · 2012 to 2022
$4.4M
The Epidemiology of Multi-Drug Resistant Enterobacteriaceae Infections in ChildreK08AI112506 · NIAID · RUSH UNIVERSITY MEDICAL CENTER · PI LOGAN, LATANIA K. · 2014 to 2018
$916k
NIAID NIH HHS K08 AI112506NIAID NIH HHS R01 AI063517NIAID NIH HHS R01 AI072219NIAID NIH HHS R01 AI100560
6 · The paper itself

Abstract

We report the first case of a child in the United States infected with an organism producing a Verona Integron-Encoded Metallo-β-Lactamase. This child succumbed to a ventilator-associated pneumonia caused by a Klebsiella pneumoniae producing this resistance mechanism.

Indexed as

beta-LactamasesChild, PreschoolDrug Resistance, BacterialFatal OutcomeHumansIntegronsKlebsiella InfectionsKlebsiella pneumoniaeMalePneumonia, Ventilator-AssociatedUnited Statesbeta-LactamasescarbapenemaseCREmetallo-β-lactamasepediatricsVIM

Identifiers

PMID27147714
PMCPMC5125454
OpenAlexW2346420494

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.