Evidence map›Paper›PMID 27147670›Full record

ReviewAmerican journal of physiology. Renal physiology2016

Recent advances in renal hypoxia: insights from bench experiments and computer simulations.

Anita T Layton

Abstract readReview
In one paragraph

Review in American journal of physiology. Renal physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Article
  3. Morroniside inJournal of clinical biochemistry and nutrition · 2026
    Article
  4. Feline Renal Cortical Thickness-Aortic Diameter Ratio in Healthy Versus Diseased Kidneys: Comparative Ultrasonographic Evaluation.Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association · 2025
    Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Heme Oxygenase 1: A Defensive Mediator in Kidney Diseases.International journal of molecular sciences · 2021
    Review
  10. Article
  11. Roles of Nrf2 in Protecting the Kidney from Oxidative Damage.International journal of molecular sciences · 2020
    Review
  12. Article
  13. Autophagy in renal tubular injury and repair.Acta physiologica (Oxford, England) · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Anita T LaytonDepartment of Mathematics, Duke University, North Carolina alayton@math.duke.edu.

Funding

Unraveling Kidney Physiology, Pathophysiology & Therapeutics: A Modeling ApproachR01DK106102 · NIDDK · DUKE UNIVERSITY · PI LAYTON, ANITA · 2016 to 2019
$1.4M
NIDDK NIH HHS R01 DK106102
6 · The paper itself

Abstract

The availability of oxygen in renal tissue is determined by the complex interactions among a host of processes, including renal blood flow, glomerular filtration, arterial-to-venous oxygen shunting, medullary architecture, Na(+) transport, and oxygen consumption. When this delicate balance is disrupted, the kidney may become susceptible to hypoxic injury. Indeed, renal hypoxia has been implicated as one of the major causes of acute kidney injury and chronic kidney diseases. This review highlights recent advances in our understanding of renal hypoxia; some of these studies were published in response to a recent Call for Papers of this journal: Renal Hypoxia.

Indexed as

Acute Kidney InjuryAnimalsComputer SimulationHumansHypoxiaKidney DiseasesOxygen ConsumptionRenal Insufficiency, Chronichypoxiaoxygen

Identifiers

PMID27147670
PMCPMC4967163

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.