Evidence map›Paper›PMID 27147615›Full record

ArticleSexually transmitted infections2017

Semen says: assessing the accuracy of adolescents' self-reported sexual abstinence using a semen Y-chromosome biomarker.

Janet E Rosenbaum, Jonathan M Zenilman, Eve Rose, Gina M Wingood, Ralph J DiClemente

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Sexually transmitted infections, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00633906 (Reducing HIV Risk in Female Teens), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.9field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00633906 nacompletednot on this map

Reducing HIV Risk in Female Teens: A Tailored Approach

TypeinterventionalSponsorEmory UniversityRan2002 to 2005Enrolled715ConditionsHIV Infections, Sexually Transmitted DiseasesArmsHORIZONS HIV Intervention, enhanced standard-of-care
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Inconsistencies in Adolescent Self-Reported Sexual Behavior: Experience from Four Randomized Controlled Trials.Prevention science : the official journal of the Society for Prevention Research · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Janet E RosenbaumDepartment of Epidemiology, School of Public Health, SUNY Downstate Medical Center, Brooklyn, New York, USA.
Jonathan M ZenilmanDepartment of Infectious Diseases, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA.
Eve RoseBehavioural Sciences and Health Education, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
Gina M WingoodBehavioural Sciences and Health Education, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
Ralph J DiClementeBehavioural Sciences and Health Education, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
Emory University · USJohns Hopkins University · USSUNY Downstate Health Sciences University · US

Funding

REDUCING HIV RISK IN FEMALE TEENS: A TAILORED APPROACHR01MH061210 · NIMH · EMORY UNIVERSITY · PI DICLEMENTE, RALPH J · 1999 to 2004
$2.6M
NIMH NIH HHS R01 MH061210
6 · The paper itself

Abstract

objectiveResearchers often assess condom use only among participants who report recent sexual behaviour, excluding participants who report no recent vaginal sex or who did not answer questions about their sexual behaviour, but self-reported sexual behaviour may be inaccurate. This study uses a semen Y-chromosome biomarker to assess semen exposure among participants who reported sexual abstinence or did not report their sexual behaviour.

methodsThis prospective cohort study uses data from 715 sexually active African-American female adolescents in Atlanta, surveyed at baseline, 6 months and 12 months. Participants completed a 40 min interview and were tested for semen Y-chromosome with PCR from a self-administered vaginal swab. We predicted Y-chromosome test results from self-reported sexual behaviour using within-subject panel regression.

resultsAmong the participants who reported abstinence from vaginal sex in the past 14 days, 9.4% tested positive for semen Y-chromosome. Among item non-respondents, 6.3% tested positive for semen Y-chromosome. Women who reported abstinence and engaged in item non-response regarding their sexual behaviour had respectively 62% and 78% lower odds of testing positive for Y-chromosome (OR 0.38 (0.21 to 0.67), OR 0.22 (0.12 to 0.40)), controlling for smoking, survey wave and non-coital sexual behaviours reported during abstinence.

conclusionsAdolescents who report sexual abstinence under-report semen exposure. Research should validate self-reported sexual behaviour with biomarkers. Adolescents who engage in item non-response regarding vaginal sex test positive for semen Y-chromosome at similar rates, which supports the practice of grouping non-respondents with adolescents reporting abstinence in statistical analysis. TRIAL REGISTRATION NUMBER: NCT00633906.

Indexed as

Adolescent BehaviorSelf ReportAdolescentBiomarkersBlack or African AmericanChromosomes, Human, YFemaleHumansMalePolymerase Chain ReactionProspective StudiesSemenSexual AbstinenceSexual BehaviorUnited StatesVaginaBiomarkersADOLESCENTEPIDEMIOLOGY (GENERAL)HETEROSEXUAL BEHAVIOURSEXUAL BEHAVIOURWOMEN

Identifiers

PMID27147615
PMCPMC5097018
OpenAlexW2346347945

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.