Evidence map›Paper›PMID 27147468›Full record

ReviewCellular and molecular life sciences : CMLS2016

Regulation of actin nucleation and autophagosome formation.

Amanda S Coutts, Nicholas B La Thangue

Open access · hybridAbstract readReview
In one paragraph

Review in Cellular and molecular life sciences : CMLS, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 43 citations in OpenAlex.

  1. Review
  2. Article
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  4. Review
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  6. Review
  7. Review
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  9. Review
  10. Form and function of actin impacts actin health and aging.bioRxiv : the preprint server for biology · 2025
    Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Clinical Significance of TUBGCP4 Expression in Hepatocellular Carcinoma.Analytical cellular pathology (Amsterdam) · 2022
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Amanda S CouttsLaboratory of Cancer Biology, Medical Sciences Division, Department of Oncology, University of Oxford, Old Road Campus Research Building, Old Road Campus, Off Roosevelt Drive, Oxford, OX3 7DQ, UK.
Nicholas B La ThangueLaboratory of Cancer Biology, Medical Sciences Division, Department of Oncology, University of Oxford, Old Road Campus Research Building, Old Road Campus, Off Roosevelt Drive, Oxford, OX3 7DQ, UK. nick.lathangue@oncology.ox.ac.uk.
University of Oxford · GB

Funding

Cancer Research UK 13058Cancer Research UK 20776Cancer Research UK C300/A13058Medical Research Council G0500905Medical Research Council G1000807Medical Research Council G9400953
6 · The paper itself

Abstract

Autophagy is a process of self-eating, whereby cytosolic constituents are enclosed by a double-membrane vesicle before delivery to the lysosome for degradation. This is an important process which allows for recycling of nutrients and cellular components and thus plays a critical role in normal cellular homeostasis as well as cell survival during stresses such as starvation or hypoxia. A large number of proteins regulate various stages of autophagy in a complex and still incompletely understood series of events. In this review, we will discuss recent studies which provide a growing body of evidence that actin dynamics and proteins that influence actin nucleation play an important role in the regulation of autophagosome formation and maturation.

Indexed as

Actin-Related Protein 2-3 ComplexActinsAnimalsAutophagosomesAutophagyLysosomesMicrotubule-Associated ProteinsMyosinsActin-Related Protein 2-3 ComplexActinsMicrotubule-Associated ProteinsMyosinsActinArp2/3AutophagosomeAutophagyJMYLC3WH2

Identifiers

PMID27147468
PMCPMC4967107
OpenAlexW2346648977

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.