Trial reportLung2016
Short-Term Effect of Different Physical Exercises and Physiotherapy Combinations on Sputum Expectoration, Oxygen Saturation, and Lung Function in Young Patients with Cystic Fibrosis.
Trial report in Lung, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- Physical activity and exercise training in cystic fibrosis.The Cochrane database of systematic reviews · 2022Pooled it
- Physical exercise training for cystic fibrosis.The Cochrane database of systematic reviews · 2017Pooled it
- Short-term effects of a novel bronchial drainage device: A pilot cohort study in subjects with cystic fibrosis.Health science reports · 2022Article
- Exercise as an Airway Clearance Technique in people with Cystic Fibrosis (ExACT-CF): rationale and study protocol for a randomised pilot trial.NIHR open research · 2022Article
- Methods Used to Evaluate the Immediate Effects of Airway Clearance Techniques in Adults with Cystic Fibrosis: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2021Review
- The Fitter the Better? Cardiopulmonary Exercise Testing Can Predict Pulmonary Exacerbations in Cystic Fibrosis.Children (Basel, Switzerland) · 2021Article
- Article
- Gaming Console Home-Based Exercise for Adults with Cystic Fibrosis: Study Protocol.International journal of caring sciencesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeExercise and chest physiotherapy are integral components of cystic fibrosis (CF) care. We aimed to determine short-term effects of a combined exercise-physiotherapy intervention, using either trampoline or cycle exercises compared to billiard (sham training) on sputum production, oxygen saturation (SaO2) and short-term lung function in participants with CF.
methodsTwelve 16- to 29-year-old individuals with CF were randomly allocated to all 3 interventions on non-consecutive days of a week with exercise and physiotherapy parts lasting 30 min and breaks of 30 min after each procedure. Sputum weight (g) and lung function were measured before and after the exercise + rest and physiotherapy + rest interventions and SaO2 was measured before and after the combined interventions. Differences in outcome measures between the different exercises and combined exercise/physiotherapy regimens were analyzed by univariate multilevel linear regression.
resultsSputum expectoration during and after trampoline exercise was significantly higher than with and after billiard (P = 0.021), and tended to be higher than with and after cycling of similar cardiovascular intensity (P = 0.074). Sputum weights during and after physiotherapy were comparable among sessions, irrespective of the prior exercise or sham procedure. The increase in SaO2 was significantly higher after the combined trampoline/physiotherapy (1.7 ± 0.9%) and cycling/physiotherapy (1.8 ± 0.8%) sessions compared to billiard/physiotherapy (0.5 ± 1.8%, P = 0.011 and P = 0.007). No effects were observed on lung function.
conclusionsExercise followed by physiotherapy has an additive effect on sputum production in participants with CF and leads to improved oxygen saturation. Exercises with increased ventilation combined with mechanical vibration seem to be most efficient.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.