SynthesisEuropean radiology2017
The diagnostic performance of shear wave elastography for malignant cervical lymph nodes: A systematic review and meta-analysis.
Synthesis in European radiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04561999 (Value of Ultrasound Elastography in Characterization of Superficial Lymphadenopathy), which is not on this map. Cited by 42 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Value of Ultrasound Elastography in Characterization of Superficial Lymphadenopathy
Who cites it
42 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Elastography for distinguishing lymphoma from benign and metastatic lymphadenopathy: a systematic review and Bayesian meta-analysis.Cancer imaging : the official publication of the International Cancer Imaging Society · 2026Pooled it
- Diagnostic value of supersonic shear impulse elastography for malignant cervical lymph nodes: a Bayesian analysis.Ultrasonography (Seoul, Korea) · 2022Pooled it
- Pooled it
- Diagnostic Accuracy of Multiparametric Ultrasound Versus Cross-Sectional Imaging for Differentiating Benign and Malignant Cervical Lymph Nodes: A Histopathology-Referenced Retrospective Study.Diagnostics (Basel, Switzerland) · 2026Article
- Seeing Angiogenesis: Multiparametric Ultrasound as a Non-Invasive Window into the Vascularization Status of Cervical Lymph Nodes in Head and Neck Squamous Cell Carcinoma.Medicina (Kaunas, Lithuania) · 2026Review
- Lymph Node Assessment with Multiparametric Ultrasound: Normal Values, Morphologic Patterns, and Diagnostic Algorithms.Cancers · 2026Article
- Ultrasound evaluation of pediatric lymphadenopathies: diagnostic patterns and pitfalls.Pediatric radiology · 2026Review
- Article
- Mechanical Signaling: Molecular Mechanisms, Biological Functions, Diseases, and Therapeutic Targets.MedComm · 2025Review
- Multimodal imaging of cervical lymphadenopathy: diagnostic value and clinical applications.Medicine and pharmacy reports · 2025Review
- Shear Wave Elastography for Distinguishing Cervical Lymph Node Malignancy: A Prospective, Observational Study.Biomedicines · 2025Article
- The diagnostic value of two-dimensional shear-wave elastography in identifying malignant lesions in lymph nodes: a prospective study.Scientific reports · 2025Article
- Article
- Usefulness of shear-wave elastography for detection of lymph node metastasis in esophageal and gastric cancer.World journal of gastrointestinal oncology · 2025Article
- Fisher discriminant analysis of multimodal ultrasound in diagnosis of cervical metastatic lymph nodes in papillary thyroid cancer.The Korean journal of internal medicine · 2025Article
- Preliminary study on the influencing factors of Young's modulus of viscoelastic model detected by shear wave elasticity.Frontiers in medicine · 2025Article
- Multimodality high-frequency ultrasound in the evaluation of cervical malignant lymphoma before biopsy.Future oncology (London, England) · 2024Article
- Shear wave elastography to assess stiffness of the human ovary and other reproductive tissues across the reproductive lifespan in health and disease†.Biology of reproduction · 2024Review
- Impact of Region-of-Interest Size on the Diagnostic Performance of Shear Wave Elastography in Differentiating Thyroid Nodules.Cancers · 2023Article
- Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the diagnostic performance of shear wave elastography for malignant cervical lymph nodes.
methodsWe searched the Ovid-MEDLINE and EMBASE databases for published studies regarding the use of shear wave elastography for diagnosing malignant cervical lymph nodes. The diagnostic performance of shear wave elastography was assessed using bivariate modelling and hierarchical summary receiver operating characteristic modelling. Meta-regression analysis and subgroup analysis according to acoustic radiation force impulse imaging (ARFI) and Supersonic shear imaging (SSI) were also performed.
resultsEight eligible studies which included a total sample size of 481 patients with 647 cervical lymph nodes, were included. Shear wave elastography showed a summary sensitivity of 81 % (95 % CI: 72-88 %) and specificity of 85 % (95 % CI: 70-93 %). The results of meta-regression analysis revealed that the prevalence of malignant lymph nodes was a significant factor affecting study heterogeneity (p < .01). According to the subgroup analysis, the summary estimates of the sensitivity and specificity did not differ between ARFI and SSI (p = .93).
conclusionShear wave elastography is an acceptable imaging modality for diagnosing malignant cervical lymph nodes. We believe that both ARFI and SSI may have a complementary role for diagnosing malignant cervical lymph nodes. KEY POINTS: • Shear wave elastography is acceptable modality for diagnosing malignant cervical lymph nodes. • Shear wave elastography demonstrated summary sensitivity of 81 % and specificity of 85 %. • ARFI and SSI have complementary roles for diagnosing malignant cervical lymph nodes.
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