Evidence map›Paper›PMID 27147198›Full record

SynthesisPsycho-oncology2017

Cognitive behavioral therapies for informal caregivers of patients with cancer and cancer survivors: a systematic review and meta-analysis.

Mia S O'Toole, Robert Zachariae, Megan E Renna, Douglas S Mennin, Allison Applebaum

Registry-linked trialOpen access · hybridAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Psycho-oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06991673 (Adolescent Surgery Roadmap Feasibility and Acceptability Study), which is not on this map. Cited by 41 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 4 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06991673 naenrolling by invitationnot on this mapstarted 2025, after this paper: background citation

Adolescent Surgery Roadmap Feasibility and Acceptability Study

TypeinterventionalSponsorUniversity of MichiganRan2025 to 2029Enrolled100ConditionsPediatric Surgical ProceduresArmsBehavioral Treatment
3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 4 syntheses or guidelines pooled it, 81 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Are cancer helplines effective in supporting caregivers? A systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019
    Pooled it
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  12. An evidence-based stress management intervention for allogeneic hematopoietic stem cell transplant caregivers: development, feasibility and acceptability.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2017
    Trial
  13. Article
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  18. Caregiver Experiences With an Internet-Delivered Insomnia Intervention: SHUTi-CARE Trial Primary Qualitative Analysis.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2024
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Mia S O'TooleUnit for Psychooncology and Health Psychology, Institute of Psychology and Behavioral Science, School of Business and Social Sciences, Aarhus University, Aarhus, Denmark.
Robert ZachariaeUnit for Psychooncology and Health Psychology, Aarhus University and Aarhus University Hospital, Aarhus, Denmark.
Megan E RennaDepartment of Psychology, CUNY Hunter College and the Graduate Center, New York, USA.
Douglas S MenninDepartment of Psychology, CUNY Hunter College and the Graduate Center, New York, USA.
Allison ApplebaumDepartment of Psychiatry and Behavioral Sciences, Memorial Sloan Kettering Cancer Center, New York, USA.
The Graduate Center, CUNY · USAarhus University · DKAarhus University Hospital · DKMemorial Sloan Kettering Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

objectiveInformal caregivers (ICs) of patients with cancer and cancer survivors report a number of psychological and physical complaints because of the burden associated with providing care. Given the documented effect of Cognitive Behavioral Therapy (CBT) on ICs' common psychological complaints, such as anxiety and depression, the objective was to conduct a meta-analysis on the effect of CBTs for adult ICs.

methodsA literature search was conducted in order to identify all intervention studies on adult ICs that employed at least one therapeutic component defined as a CBT component.

resultsLiterature searches revealed 36 unique records with sufficient data. These studies were subjected to meta-analyses using random effects models. A small, statistically significant effect of CBTs (Hedge's g = 0.08, p = 0.014) was revealed, which disappeared when randomized controlled trials were evaluated alone (g = 0.04, p = 0.200). A number of variables were explored as moderators. Only the percentage of female participants was positively associated with the effect size.

conclusionsBased on the negligible effect of CBTs across outcomes, future studies should consider moving beyond traditional CBT methods as these do not appear efficacious. It is suggested that future interventions orient towards advances in the basic affective sciences and derived therapies in order to better understand and treat the emotional struggles experienced by ICs. © 2016 The Authors. Psycho-Oncology published by John Wiley & Sons Ltd.

Indexed as

Mental HealthAdaptation, PsychologicalAdultAnxietyAnxiety DisordersCancer SurvivorsCaregiversCognitive Behavioral TherapyDepressionDepressive DisorderFemaleHumansPsychotherapycancercaregiversCBToncologypsychological interventionpsychotherapy

Identifiers

PMID27147198
PMCPMC5412844
OpenAlexW2346295523

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.