ArticleInternational wound journal2017
Essential oils and metal ions as alternative antimicrobial agents: a focus on tea tree oil and silver.
Article in International wound journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Comparison of the efficacy of tea tree (Parasitology · 2020Pooled it
- Tea tree oil action on human corneal epithelial cells biological activity.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Optimizing Poultry Nutrition to CombatMicroorganisms · 2024Review
- Impact of plant monoterpenes on insect pest management and insect-associated microbes.Heliyon · 2024Review
- Antimycobacterial Activity of Essential Oils from BulgarianPharmaceutics · 2024Article
- Enhancing Antibacterial Efficacy: Synergistic Effects ofFoods (Basel, Switzerland) · 2024Article
- An Overview of Wound Dressing Materials.Pharmaceuticals (Basel, Switzerland) · 2024Review
- Preparing and evaluating the anti-microbial effect ofJournal of family medicine and primary care · 2024Article
- Effects of essential oils on egg production and feed efficiency as influenced by laying hen breed: A meta-analysis.Veterinary world · 2024Article
- Enrichment of Cellulose Acetate Nanofibrous Scaffolds with Retinyl Palmitate and Clove Essential Oil for Wound Healing Applications.ACS omega · 2023Article
- Characterisation of physicochemical parameters and antibacterial properties of New Caledonian honeys.PloS one · 2023Article
- Novel Formula of Antiprotozoal Mixtures.Antibiotics (Basel, Switzerland) · 2022Article
- Challenges and innovations in treating chronic and acute wound infections: from basic science to clinical practice.Burns & trauma · 2022Review
- Combined effect of thyme and clove phenolic compounds onFrontiers in microbiology · 2022Article
- Evaluation of Effectiveness of a Toothpaste Containing Tea Tree Oil and Ethanolic Extract of Propolis on the Improvement of Oral Health in Patients Using Removable Partial Dentures.Molecules (Basel, Switzerland) · 2021Article
- Antibacterial Activity and Mode of Action of β-caryophyllene onPolish journal of microbiology · 2020Article
- Antimicrobial Silver Nanoparticles for Wound Healing Application: Progress and Future Trends.Materials (Basel, Switzerland) · 2019Review
- Anti-fungal bandages containing cinnamon extract.International wound journal · 2019Article
- Treatment Strategies for Infected Wounds.Molecules (Basel, Switzerland) · 2018Review
- Bacterial resistance to antibiotic alternatives: a wolf in sheep's clothing?Animal frontiers : the review magazine of animal agriculture · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The increasing occurrence of hospital-acquired infections and the emerging problems posed by antibiotic-resistant microbial strains have both contributed to the escalating cost of treatment. The presence of infection at the wound site can potentially stall the healing process at the inflammatory stage, leading to the development of a chronic wound. Traditional wound treatment regimes can no longer cope with the complications posed by antibiotic-resistant strains; hence, there is a need to explore the use of alternative antimicrobial agents. Pre-antibiotic compounds, including heavy metal ions and essential oils, have been re-investigated for their potential use as effective antimicrobial agents. Essential oils have potent antimicrobial, antifungal, antiviral, anti-inflammatory, antioxidant and other beneficial therapeutic properties. Similarly, heavy metal ions have also been used as disinfecting agents because of their broad spectrum activities. Both of these alternative antimicrobials interact with many different intracellular components, thereby resulting in the disruption of vital cell functions and eventually cell death. This review will discuss the application of essential oils and heavy metal ions, particularly tea tree oil and silver ions, as alternative antimicrobial agents for the treatment of chronic, infected wounds.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.