Evidence map›Paper›PMID 27146169›Full record

ArticleEuropean journal of applied physiology2016

Physical exercise associated with improved BMD independently of sex and vitamin D levels in young adults.

Rune Tønnesen, Peter Schwarz, Peter Hambak Hovind, Lars Thorbjørn Jensen

Open access · hybridAbstract readControlled Clinical Trial
In one paragraph

Article in European journal of applied physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 32 citations in OpenAlex.

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  18. Determinants of bone mineral density in young Australian women; results from the Safe-D study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Rune TønnesenDepartment of Clinical Physiology and Nuclear Medicine, Rigshospitalet, Nordre Ringvej 57, Glostrup, 2600, Copenhagen, Denmark. rune@tonnesen.org.
Peter SchwarzDepartment of Endocrinology PE and Research Centre of Ageing and Osteoporosis, Rigshospitalet, Copenhagen, Denmark.
Peter Hambak HovindDepartment of Clinical Physiology and Nuclear Medicine, Rigshospitalet, Nordre Ringvej 57, Glostrup, 2600, Copenhagen, Denmark.
Lars Thorbjørn JensenDepartment of Clinical Physiology and Nuclear Medicine, University Hospital of Herlev, Copenhagen, Denmark.
Rigshospitalet · DKUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeYoung men and women accrue the majority of their bone mass in their teens and twenties, where their bone mass peaks (PBM), yet little is known about the roles of physical exercise, vitamin D levels and bone mineral density (BMD) near PBM.

methodsTo comparatively examine the effect of physical exercise and two vitamin D levels (insufficient s-25[OH]D <50 nmol/L and sufficient s-25[OH]D >80 nmol/L) on the BMD measured at the femoral neck, total hip (bilaterally) and the lumbar spine (L2-L4) in male and female participants approaching PBM.

resultsThe insufficient s-25[OH]D group, median age 21.6 (19.8-22.8) years, and BMI 24.2 ± 5.0 kg/m(2) had BMD 0.10 (0.03, 0.17) g/cm(2) (p = 0.008) lower at all DXA-scan sites compared to the sufficient s-25[OH]D group, median age 19.5 (19.0-22.3) years, and BMI of 22.6 ± 1.8 kg/m(2). Exercise was positively associated with the BMD at all DXA-scan sites (p trend = 0.0001) and with equal benefit; there was no interaction between exercise and the DXA-scan site (p = 0.09). The male participants did not have a systematically higher BMD than the female participants for all scan sites; only for hips total and femoral neck bilaterally, while it was equal at the lumbar spine.

conclusionThe BMD in young healthy adults is associated with physical exercise, independent of sex and s-25[OH]D status. A sufficient s-25[OH]D status was systematically associated with a higher BMD for all levels of exercise. For both sexes and vitamin D levels exercise was equally positively associated with BMD.

Indexed as

AdolescentAdultBone DensityExerciseFemaleHumansMalePhysical Conditioning, HumanSex FactorsTreatment OutcomeVitamin DYoung AdultVitamin DBMDBonePhysical exerciseSexVitamin DYoung adults

Identifiers

PMID27146169
PMCPMC4911375
OpenAlexW2346862777

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.