Evidence map›Paper›PMID 27146145›Full record

ArticleArchives of toxicology2017

Accelerated telomere shortening in peripheral blood lymphocytes after occupational polychlorinated biphenyls exposure.

Susanne Ziegler, Thomas Schettgen, Fabian Beier, Stefan Wilop, Natalia Quinete, Andre Esser, Behzad Kharabi Masouleh, Monica S V Ferreira, Lucia Vankann, Peter Uciechowski and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Archives of toxicology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 51 citations in OpenAlex.

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  15. Occupational exposure to particulate matters and telomere length.Environmental science and pollution research international · 2018
    Article
  16. Article
  17. Long-term Persistent Organic Pollutants Exposure Induced Telomere Dysfunction and Senescence-Associated Secretary Phenotype.The journals of gerontology. Series A, Biological sciences and medical sciences · 2018
    Article
  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Susanne ZieglerDepartment of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Medical Faculty, RWTH Aachen University, Aachen, Germany.
Thomas SchettgenInstitute for Occupational and Social Medicine, University Hospital of the RWTH Aachen, RWTH Aachen University, Aachen, Germany.
Fabian BeierDepartment of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Medical Faculty, RWTH Aachen University, Aachen, Germany.
Stefan WilopDepartment of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Medical Faculty, RWTH Aachen University, Aachen, Germany.
Natalia QuineteInstitute for Occupational and Social Medicine, University Hospital of the RWTH Aachen, RWTH Aachen University, Aachen, Germany.
Andre EsserInstitute for Occupational and Social Medicine, University Hospital of the RWTH Aachen, RWTH Aachen University, Aachen, Germany.
Behzad Kharabi MasoulehDepartment of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Medical Faculty, RWTH Aachen University, Aachen, Germany.
Monica S V FerreiraDepartment of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Medical Faculty, RWTH Aachen University, Aachen, Germany.
Lucia VankannDepartment of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Medical Faculty, RWTH Aachen University, Aachen, Germany.
Peter UciechowskiInstitute of Immunology, RWTH Aachen University, Aachen, Germany.
Lothar RinkInstitute of Immunology, RWTH Aachen University, Aachen, Germany.
Thomas KrausInstitute for Occupational and Social Medicine, University Hospital of the RWTH Aachen, RWTH Aachen University, Aachen, Germany.
Tim H BrümmendorfDepartment of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Medical Faculty, RWTH Aachen University, Aachen, Germany.
Patrick ZieglerDepartment of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Medical Faculty, RWTH Aachen University, Aachen, Germany. pziegler@ukaachen.de.
RWTH Aachen University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polychlorinated biphenyls (PCBs) are organochlorine pollutants with a worldwide dissemination. We examined telomere length (TL) in peripheral blood cells of 207 individuals with a high body burden of PCBs due to occupational exposure in a transformer recycling company. Whereas TL in granulocytes was not affected, the age-adjusted TL in lymphocytes (∆TL

Indexed as

BiotransformationCarcinogens, EnvironmentalCell ProliferationCells, CulturedCohort StudiesDrug ResiduesFemaleGene Expression Regulation, EnzymologicGermanyHumansImmunologic SurveillanceKineticsLymphocytesMaleOccupational ExposurePolychlorinated Biphenyls2,4,4'-trichlorobiphenylCarcinogens, EnvironmentalPolychlorinated BiphenylsTelomeraseLymphocytesOccupational exposurePolychlorinated biphenylsTelomere

Identifiers

PMID27146145
PMCPMC5225163
OpenAlexW2347193990

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.