Evidence map›Paper›PMID 27146044›Full record

ArticleBMC psychiatry2016

A history of childhood trauma is associated with slower improvement rates: Findings from a one-year follow-up study of patients with a first-episode psychosis.

Monica Aas, Ole A Andreassen, Sofie R Aminoff, Ann Færden, Kristin L Romm, Ragnar Nesvåg, Akiah O Berg, Carmen Simonsen, Ingrid Agartz, Ingrid Melle

Open access · goldAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC psychiatry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 3 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 3 syntheses or guidelines pooled it, 85 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Observational
  16. Maternal childhood trauma and observed maternal care behaviors with 4-month-old infants.Psychological trauma : theory, research, practice and policy · 2024
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Monica AasDivision of Mental Health and Addiction, Institute of Clinical Medicine, NORMENT K.G Jebsen Centre for Psychosis Research, TOP study group, University of Oslo and Oslo University Hospital, Bygg 49, Ullevål sykehus, PO Box 4956, Nydalen, 0424, Oslo, Norway. monica.aas@medisin.uio.no.
Ole A AndreassenDivision of Mental Health and Addiction, Institute of Clinical Medicine, NORMENT K.G Jebsen Centre for Psychosis Research, TOP study group, University of Oslo and Oslo University Hospital, Bygg 49, Ullevål sykehus, PO Box 4956, Nydalen, 0424, Oslo, Norway.
Sofie R AminoffDivision of Mental Health and Addiction, Institute of Clinical Medicine, NORMENT K.G Jebsen Centre for Psychosis Research, TOP study group, University of Oslo and Oslo University Hospital, Bygg 49, Ullevål sykehus, PO Box 4956, Nydalen, 0424, Oslo, Norway.
Ann FærdenDivision of Mental Health and Addiction, Institute of Clinical Medicine, NORMENT K.G Jebsen Centre for Psychosis Research, TOP study group, University of Oslo and Oslo University Hospital, Bygg 49, Ullevål sykehus, PO Box 4956, Nydalen, 0424, Oslo, Norway.
Kristin L RommDivision of Mental Health and Addiction, Institute of Clinical Medicine, NORMENT K.G Jebsen Centre for Psychosis Research, TOP study group, University of Oslo and Oslo University Hospital, Bygg 49, Ullevål sykehus, PO Box 4956, Nydalen, 0424, Oslo, Norway.
Ragnar NesvågDepartment of Genetics, Environment and Mental Health, Norwegian Institute of Public Health, Oslo, Norway.
Akiah O BergDivision of Mental Health and Addiction, Institute of Clinical Medicine, NORMENT K.G Jebsen Centre for Psychosis Research, TOP study group, University of Oslo and Oslo University Hospital, Bygg 49, Ullevål sykehus, PO Box 4956, Nydalen, 0424, Oslo, Norway.
Carmen SimonsenDivision of Mental Health and Addiction, Institute of Clinical Medicine, NORMENT K.G Jebsen Centre for Psychosis Research, TOP study group, University of Oslo and Oslo University Hospital, Bygg 49, Ullevål sykehus, PO Box 4956, Nydalen, 0424, Oslo, Norway.
Ingrid AgartzDivision of Mental Health and Addiction, Institute of Clinical Medicine, NORMENT K.G Jebsen Centre for Psychosis Research, TOP study group, University of Oslo and Oslo University Hospital, Bygg 49, Ullevål sykehus, PO Box 4956, Nydalen, 0424, Oslo, Norway.
Ingrid MelleDivision of Mental Health and Addiction, Institute of Clinical Medicine, NORMENT K.G Jebsen Centre for Psychosis Research, TOP study group, University of Oslo and Oslo University Hospital, Bygg 49, Ullevål sykehus, PO Box 4956, Nydalen, 0424, Oslo, Norway.
Oslo University Hospital · NOUniversity of Oslo · NOAkershus University Hospital · NODiakonhjemmet Hospital · NONorwegian Institute of Public Health · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to investigate whether childhood trauma was associated with more severe clinical features in patients with first-episode psychosis, both at the initial assessment and after one year.

methodsNinety-six patients with a first-episode of a DSM-IV diagnosis of psychosis, in addition to 264 healthy controls from the same catchment area, were recruited to the TOP NORMENT study. A history of childhood trauma was obtained using the Childhood Trauma Questionnaire (CTQ). Function and symptom severity were measured using the Global Assessment of Functioning (GAF) Scale divided into function (GAF-F) and symptoms (GAF-S), the Positive and Negative Syndrome Scale (PANSS) and the Young Mania Rating Scale (YMRS). All clinical assessments were completed at two time points: At an initial assessment within the first year of initiating treatment for psychosis and after one year.

resultsChildhood trauma was associated with significantly reduced global functioning and more severe clinical symptoms at both baseline and follow-up, whereas emotional neglect was associated with a significantly reduced improvement rate for global functioning (GAF-F) over the follow-up period.

conclusionOur data indicate that patients with first-episode psychosis who report a history of childhood trauma constitute a subgroup characterized by more severe clinical features over the first year of treatment, as well as slower improvement rates.

Indexed as

Severity of Illness IndexAdolescentAdultChild Behavior DisordersFemaleFollow-Up StudiesHumansMalePsychotic DisordersRisk Factors

Identifiers

PMID27146044
PMCPMC4855869
OpenAlexW2345956444

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.