ArticleScientific reports2016
Wearable 3-D Photoacoustic Tomography for Functional Brain Imaging in Behaving Rats.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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Who cites it
37 citing papers in PubMed.
- Optoacoustic brain imaging: A systematic review and field mapping.Photoacoustics · 2026Article
- Advanced methods of wearable ultrasound and photoacoustic imaging devices: A review.Photoacoustics · 2026Article
- Ultrawideband high density polymer-based spherical array for real-time functional optoacoustic micro-angiography.Light, science & applications · 2025Article
- Emerging Wearable Acoustic Sensing Technologies.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Label-free photoacoustic computed tomography of visually evoked responses in the primary visual cortex and four subcortical retinorecipient nuclei of anesthetized mice.Neurophotonics · 2024Article
- Photoacoustic microscopy for real-time monitoring of near-infrared optical absorbers inside biological tissue.Journal of biomedical optics · 2024Article
- Deep learning on photoacoustic tomography to remove image distortion due to inaccurate measurement of the scanning radius.Biomedical optics express · 2023Article
- A Miniature Multi-Functional Photoacoustic Probe.Micromachines · 2023Article
- Application of photoacoustic computed tomography in biomedical imaging: A literature review.Bioengineering & translational medicine · 2023Review
- Functional imaging of the exposed brain.Frontiers in neuroscience · 2023Review
- Cross-Ray Ultrasound Tomography and Photoacoustic Tomography of Cerebral Hemodynamics in Rodents.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Article
- Practical review on photoacoustic computed tomography using curved ultrasound array transducer.Biomedical engineering letters · 2022Review
- Advanced high resolution three-dimensional imaging to visualize the cerebral neurovascular network in stroke.International journal of biological sciences · 2022Review
- Dual-model wearable photoacoustic microscopy and electroencephalograph: study of neurovascular coupling in anesthetized and freely moving rats.Biomedical optics express · 2021Article
- Activity-based photoacoustic probe for biopsy-free assessment of copper in murine models of Wilson's disease and liver metastasis.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Emerging imaging methods to study whole-brain function in rodent models.Translational psychiatry · 2021Review
- Review of consensus test methods in medical imaging and current practices in photoacoustic image quality assessment.Journal of biomedical optics · 2021Review
- Photoacoustic computed tomography for functional human brain imaging [Invited].Biomedical optics express · 2021Review
- Perspective on fast-evolving photoacoustic tomography.Journal of biomedical optics · 2021Article
- Oxygen Saturation Imaging Using LED-Based Photoacoustic System.Sensors (Basel, Switzerland) · 2021Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Understanding the relationship between brain function and behavior remains a major challenge in neuroscience. Photoacoustic tomography (PAT) is an emerging technique that allows for noninvasive in vivo brain imaging at micrometer-millisecond spatiotemporal resolution. In this article, a novel, miniaturized 3D wearable PAT (3D-wPAT) technique is described for brain imaging in behaving rats. 3D-wPAT has three layers of fully functional acoustic transducer arrays. Phantom imaging experiments revealed that the in-plane X-Y spatial resolutions were ~200 μm for each acoustic detection layer. The functional imaging capacity of 3D-wPAT was demonstrated by mapping the cerebral oxygen saturation via multi-wavelength irradiation in behaving hyperoxic rats. In addition, we demonstrated that 3D-wPAT could be used for monitoring sensory stimulus-evoked responses in behaving rats by measuring hemodynamic responses in the primary visual cortex during visual stimulation. Together, these results show the potential of 3D-wPAT for brain study in behaving rodents.
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