Evidence map›Paper›PMID 27146001›Full record

ArticleClinical and vaccine immunology : CVI2016

Modified Vaccinia Ankara Virus Vaccination Provides Long-Term Protection against Nasal Rabbitpox Virus Challenge.

Dorothy I Jones, Charles E McGee, Christopher J Sample, Gregory D Sempowski, David J Pickup, Herman F Staats

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical and vaccine immunology : CVI, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dorothy I JonesDepartment of Pathology, Duke University Medical Center, Durham, North Carolina, USA.
Charles E McGeeDepartment of Medicine, Duke University Medical Center, Durham, North Carolina, USA.
Christopher J SampleDepartment of Medicine, Duke University Medical Center, Durham, North Carolina, USA.
Gregory D SempowskiDepartment of Pathology, Duke University Medical Center, Durham, North Carolina, USA Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA.
David J PickupDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, USA.
Herman F StaatsDepartment of Pathology, Duke University Medical Center, Durham, North Carolina, USA Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA herman.staats@duke.edu.ORCID 0000-0003-1039-1087

Funding

Regional Biocontainment Laboratory (RBL)UC6AI058607 · NIAID · DUKE UNIVERSITY · PI WILLIAMS, R SANDERS · 2003 to 2005
$16.3M
Mucosal vaccination to protect against HIV-1 infection at mucosal sitesR01AI102747 · NIAID · DUKE UNIVERSITY · PI STAATS, HERMAN F · 2012 to 2015
$2.3M
NIAID NIH HHS R01 AI102747NIAID NIH HHS UC6 AI058607
6 · The paper itself

Abstract

Modified vaccinia Ankara virus (MVA) is a smallpox vaccine candidate. This study was performed to determine if MVA vaccination provides long-term protection against rabbitpox virus (RPXV) challenge, an animal model of smallpox. Two doses of MVA provided 100% protection against a lethal intranasal RPXV challenge administered 9 months after vaccination.

Indexed as

AnimalsDisease Models, AnimalFemaleImmunization ScheduleRabbitsSmallpoxSmallpox VaccineSurvival AnalysisVaccinia virusSmallpox Vaccine

Identifiers

PMID27146001
PMCPMC4933771

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.