Evidence map›Paper›PMID 27144897›Full record

ArticleRNA biology2016

STarMirDB: A database of microRNA binding sites.

William Rennie, Shaveta Kanoria, Chaochun Liu, Bibekanand Mallick, Dang Long, Adam Wolenc, C Steven Carmack, Jun Lu, Ye Ding

Abstract read
In one paragraph

Article in RNA biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. MicroRNA-190b Targets RFWD3 in Estrogen Receptor-Positive Breast Cancer.Breast cancer : basic and clinical research · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Circulating MicroRNAs as Cancer Biomarkers in Liquid Biopsies.Advances in experimental medicine and biology · 2022
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

William Renniea Wadsworth Center, New York State Department of Health , Center for Medical Science , Albany , NY , USA.
Shaveta Kanoriaa Wadsworth Center, New York State Department of Health , Center for Medical Science , Albany , NY , USA.
Chaochun Liua Wadsworth Center, New York State Department of Health , Center for Medical Science , Albany , NY , USA.
Bibekanand Mallicka Wadsworth Center, New York State Department of Health , Center for Medical Science , Albany , NY , USA.
Dang Longa Wadsworth Center, New York State Department of Health , Center for Medical Science , Albany , NY , USA.
Adam Wolenca Wadsworth Center, New York State Department of Health , Center for Medical Science , Albany , NY , USA.
C Steven Carmacka Wadsworth Center, New York State Department of Health , Center for Medical Science , Albany , NY , USA.
Jun Lua Wadsworth Center, New York State Department of Health , Center for Medical Science , Albany , NY , USA.
Ye Dinga Wadsworth Center, New York State Department of Health , Center for Medical Science , Albany , NY , USA.

Funding

Novel Approaches to Mammalian MicroRNA Target PredictionR01GM099811 · NIGMS · WADSWORTH CENTER · PI DING, YE, LU, JUN · 2012 to 2015
$2.4M
Quantitative Modeling of MicroRNA:Target Interactions in Cell Fate TransitionR01GM116855 · NIGMS · WADSWORTH CENTER · PI DING, YE, LU, JUN · 2016 to 2019
$2.2M
NIGMS NIH HHS R01 GM099811NIGMS NIH HHS R01 GM116855
6 · The paper itself

Abstract

microRNAs (miRNAs) are an abundant class of small endogenous non-coding RNAs (ncRNAs) of ∼22 nucleotides (nts) in length. These small regulatory molecules are involved in diverse developmental, physiological and pathological processes. miRNAs target mRNAs (mRNAs) for translational repression and/or mRNA degradation. Predictions of miRNA binding sites facilitate experimental validation of miRNA targets. Models developed with data from CLIP studies have been used for predictions of miRNA binding sites in the whole transcriptomes of human, mouse and worm. The prediction results have been assembled into STarMirDB, a new database of miRNA binding sites available at http://sfold.wadsworth.org/starmirDB.php . STarMirDB can be searched by miRNAs or mRNAs separately or in combination. The search results are categorized into seed and seedless sites in 3' UTR, CDS and 5' UTR. For each predicted site, STarMirDB provides a comprehensive list of sequence, thermodynamic and target structural features that are known to influence miRNA: target interaction. A high resolution PDF diagram of the conformation of the miRNA:target hybrid is also available for visualization and publication. The results of a database search are available through both an interactive viewer and downloadable text files.

Indexed as

Databases, Nucleic Acid3' Untranslated Regions5' Untranslated RegionsAnimalsBinding SitesCaenorhabditis elegansGene Expression RegulationHumansMiceMicroRNAsRNA, MessengerRNA StabilitySequence Analysis, RNASoftwareUser-Computer Interface3' Untranslated Regions5' Untranslated RegionsMicroRNAsRNA, MessengerBinding site predictionCLIPmicroRNAseedless siteseed site

Identifiers

PMID27144897
PMCPMC4962797

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.