ArticleAngewandte Chemie (International ed. in English)2016
Remote Control of T Cell Activation Using Magnetic Janus Particles.
Article in Angewandte Chemie (International ed. in English), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Decoding mechanoregulation in immunological synapses using biomimetic artificial cells.Nature methods · 2026Article
- Remote-controlled mechanical and directional motions of photoswitchable DNA condensates.Nature communications · 2025Article
- Multimodal probing of T-cell recognition with hexapod heterostructures.Nature methods · 2024Article
- Bidirectional and Stepwise Rotation of Cells and Particles Using Induced Charge Electroosmosis Vortexes.Biosensors · 2024Article
- Optoelectronic Trajectory Reconfiguration and Directed Self-Assembly of Self-Propelling Electrically Powered Active Particles.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- A Magnetically and Electrically Powered Hybrid Micromotor in Conductive Solutions: Synergistic Propulsion Effects and Label-Free Cargo Transport and Sensing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- Mechanically Optimize T Cells Activation by Spiky Nanomotors.Frontiers in bioengineering and biotechnology · 2022Article
- Translatory and rotatory motion of exchange-bias capped Janus particles controlled by dynamic magnetic field landscapes.Scientific reports · 2021Article
- Magnetic systems for cancer immunotherapy.Acta pharmaceutica Sinica. B · 2021Review
- The Energy Conversion behind Micro-and Nanomotors.Micromachines · 2021Review
- Functionalization of hybrid surface microparticles for in vitro cellular antigen classification.Analytical and bioanalytical chemistry · 2021Article
- Biofunctional Janus particles promote phagocytosis of tumor cells by macrophages.Chemical science · 2020Article
- Janus particles: design, preparation, and biomedical applications.Materials today. Bio · 2019Review
- Interrogating Cellular Functions with Designer Janus Particles.Chemistry of materials : a publication of the American Chemical Society · 2017Article
- Bioengineering of Artificial Antigen Presenting Cells and Lymphoid Organs.Theranostics · 2017Review
- Turning Diamagnetic Microbes into Multinary Micro-Magnets: Magnetophoresis and Spatio-Temporal Manipulation of Individual Living Cells.Scientific reports · 2016Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
We report a strategy for using magnetic Janus microparticles to control the stimulation of T cell signaling with single-cell precision. To achieve this, we designed Janus particles that are magnetically responsive on one hemisphere and stimulatory to T cells on the other side. By manipulating the rotation and locomotion of Janus particles under an external magnetic field, we could control the orientation of the particle-cell recognition and thereby the initiation of T cell activation. This study demonstrates a step towards employing anisotropic material properties of Janus particles to control single-cell activities without the need of complex magnetic manipulation devices.
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Registered trials
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