Evidence map›Paper›PMID 27144350›Full record

ArticleNature2016

Depression: Ketamine steps out of the darkness.

Roberto Malinow

Abstract readComment
In one paragraph

Article in Nature, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Trial
  2. Potential Role of Bmal1 in Lipopolysaccharide-Induced Depression-Like Behavior and its Associated "Inflammatory Storm".Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2024
    Article
  3. Article
  4. Article
  5. Astrocytic GABANeuroscience bulletin · 2020
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Roberto MalinowDepartment of Neurosciences, School of Medicine, and in the Section of Neurobiology, Division of Biology, University of California, San Diego, La Jolla, California 92093, USA.

Funding

MECHANISMS OF SYNAPTIC LTP--SILENT SYNAPSESR01MH049159 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MALINOW, ROBERTO · 1997 to 2019
$4.7M
Novel roles by glutamatergic receptors in the synaptic effects of beta amyloidR01AG032132 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MALINOW, ROBERTO · 2008 to 2017
$4.5M
A Synaptic Locus Controlling Behavioral DepressionR01MH091119 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MALINOW, ROBERTO · 2011 to 2020
$3.9M
NIA NIH HHS R01 AG032132NIMH NIH HHS R01 MH049159NIMH NIH HHS R01 MH091119
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAntidepressive AgentsFemaleKetamineMale6-hydroxynorketamineAntidepressive AgentsKetamine

Identifiers

PMID27144350
PMCPMC5102012

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.