Evidence map›Paper›PMID 27144177›Full record

ReviewBioMed research international2016

Chlamydia trachomatis Infection in Pregnancy: The Global Challenge of Preventing Adverse Pregnancy and Infant Outcomes in Sub-Saharan Africa and Asia.

Kristina Adachi, Karin Nielsen-Saines, Jeffrey D Klausner

Open access · hybridAbstract readReview
In one paragraph

Review in BioMed research international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 11 pooled it
9.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 11 syntheses or guidelines pooled it, 115 citations in OpenAlex.

  1. Characteristics of longitudinal maternal health studies in sub-Saharan Africa: A systematic mapping of literature between 2012 and 2022.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
    Pooled it
  2. Pooled it
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  4. Sexually Transmitted Infections Treatment Guidelines, 2021.MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports · 2021
    Guideline
  5. Pooled it
  6. Pooled it
  7. Interventions for preventing ophthalmia neonatorum.The Cochrane database of systematic reviews · 2020
    Pooled it
  8. Pooled it
  9. Pooled it
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  11. Treatment of Neonatal Chlamydial Conjunctivitis: A Systematic Review and Meta-analysis.Journal of the Pediatric Infectious Diseases Society · 2018
    Pooled it
  12. Trial
  13. Article
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  16. Review
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  20. Chlamydia trachomatis prevalence in females in São Paulo, Brazil: 11 years' surveillance of the infection.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023
    Article

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Kristina AdachiDepartment of Pediatrics, David Geffen School of Medicine, UCLA, Los Angeles, CA 90024, USA.
Karin Nielsen-SainesDepartment of Pediatrics, David Geffen School of Medicine, UCLA, Los Angeles, CA 90024, USA.
Jeffrey D KlausnerDepartment of Medicine, Division of Infectious Diseases: Global Health, David Geffen School of Medicine, UCLA, Los Angeles, CA 90024, USA; Department of Epidemiology, Jonathan and Karin Fielding School of Public Health, UCLA, Los Angeles, CA 90024, USA.ORCID 0000-0002-6922-7364
University of California, Los Angeles · USUCLA Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Screening and treatment of sexually transmitted infections (STIs) in pregnancy represents an overlooked opportunity to improve the health outcomes of women and infants worldwide. Although Chlamydia trachomatis is the most common treatable bacterial STI, few countries have routine pregnancy screening and treatment programs. We reviewed the current literature surrounding Chlamydia trachomatis in pregnancy, particularly focusing on countries in sub-Saharan Africa and Asia. We discuss possible chlamydial adverse pregnancy and infant health outcomes (miscarriage, stillbirth, ectopic pregnancy, preterm birth, neonatal conjunctivitis, neonatal pneumonia, and other potential effects including HIV perinatal transmission) and review studies of chlamydial screening and treatment in pregnancy, while simultaneously highlighting research from resource-limited countries in sub-Saharan Africa and Asia.

Indexed as

Chlamydia trachomatisAfrica South of the SaharaAsiaChlamydia InfectionsFemaleGlobal HealthHealth PromotionHumansInfant, NewbornInfant, Newborn, DiseasesInfectious Disease Transmission, VerticalMalePregnancyPregnancy Complications, InfectiousPregnancy OutcomePrevalence

Identifiers

PMID27144177
PMCPMC4837252
OpenAlexW2323907900

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.