Evidence map›Paper›PMID 27144175›Full record

ArticleBioMed research international2016

Analyzing Dynamic Changes of Laboratory Indexes in Patients with Acute Heart Failure Based on Retrospective Study.

Yurong Wang, Lei Fu, Qian Jia, Hao Yu, Pengjun Zhang, Chunyan Zhang, Xueliang Huang, Kunlun He, Yaping Tian

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 96% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yurong WangCore Laboratory of Translational Medicine, Chinese PLA General Hospital, Beijing 100853, China; School of Medicine, Nankai University, Tianjin 300071, China.
Lei FuCore Laboratory of Translational Medicine, Chinese PLA General Hospital, Beijing 100853, China; Department of Medical Engineering, 401 Hospital of Chinese PLA, Qingdao 266071, China.
Qian JiaCore Laboratory of Translational Medicine, Chinese PLA General Hospital, Beijing 100853, China; School of Medicine, Nankai University, Tianjin 300071, China.
Hao YuComputer Section of Chinese PLA General Hospital, Beijing 100853, China.
Pengjun ZhangCore Laboratory of Translational Medicine, Chinese PLA General Hospital, Beijing 100853, China.
Chunyan ZhangCore Laboratory of Translational Medicine, Chinese PLA General Hospital, Beijing 100853, China.
Xueliang HuangCore Laboratory of Translational Medicine, Chinese PLA General Hospital, Beijing 100853, China.
Kunlun HeCore Laboratory of Translational Medicine, Chinese PLA General Hospital, Beijing 100853, China; Department of Cardiology, Chinese PLA General Hospital, Beijing 100853, China.
Yaping TianCore Laboratory of Translational Medicine, Chinese PLA General Hospital, Beijing 100853, China; School of Medicine, Nankai University, Tianjin 300071, China.
Chinese PLA General Hospital · CNNankai University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background. Changes of N-terminal probrain natriuretic peptide (NT-proBNP) have been studied whether in the long term or the short term in patients of acute heart failure (AHF); however, changes of NT-proBNP in the first five days and their association with other factors have not been investigated. Aims. To describe the dynamic changes of relevant laboratory indexes in the first five days between different outcomes of AHF patients and their associations. Methods and Results. 284 AHF with dynamic values recorded were analyzed. Changes of NT-proBNP, troponin T, and C-reactive protein were different between patients with different outcomes, with higher values in adverse group than in control group at the same time points (p < 0.05). Then, prognostic use and risk stratification of NT-proBNP were assessed by receiver-operating characteristic curve and logistic regression. NT-proBNP levels at day 3 showed the best prognostic power (area under the curve = 0.730, 95% confidence interval (CI): 0.657 to 0.794) and was an independent risk factor for adverse outcome (odds ratio, OR: 2.185, 95% CI: 1.584-3.015). Classified changes of NT-proBNP may be predictive for adverse outcomes in AHF patients. Conclusions. Sequential monitoring of laboratory indexes within the first 5 days may be helpful for management of AHF patients.

Indexed as

Acute DiseaseAgedAged, 80 and overBiomarkersChinaClinical Laboratory TechniquesC-Reactive ProteinDisease ProgressionFemaleHealth Status IndicatorsHeart FailureHumansLength of StayMaleMiddle AgedNatriuretic Peptide, BrainBiomarkersC-Reactive ProteinNatriuretic Peptide, BrainPeptide Fragmentspro-brain natriuretic peptide (1-76)Troponin T

Identifiers

PMID27144175
PMCPMC4837244
OpenAlexW2335215247

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.