SynthesisBioMed research international2016
Effects of Exercise Interventions and Physical Activity Behavior on Cancer Related Cognitive Impairments: A Systematic Review.
Synthesis in BioMed research international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 76 papers, 18 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Adolescent and Young Adult Cancer Patients: Cognitive Toxicity on Survivorship (ACTS)
Cardiorespiratory Fitness, Inflammatory Biomarkers, and Cognitive Function Patterns During Treatment for Breast Cancer: a Prospective Cohort Study
Comprehensive Outcomes for After Cancer Health (COACH): the Feasibility and Impact of an MHealth Augmented Coaching Program for Self-Management in Cancer Survivors
A Remotely-Delivered, Combined Exercise Training Program for Cognitive Function in Women Living With and Beyond Breast Cancer: A Feasibility Study
Who cites it
76 citing papers in PubMed, 18 syntheses or guidelines pooled it.
- The effect of exercise on cognitive function in breast cancer survivors: systematic review and meta-analysis of randomized controlled trials.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Pooled it
- The effect of non-pharmacological interventions on cognitive function in cancer: an overview of systematic reviews.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Pooled it
- Moderators of exercise effects on self-reported cognitive functioning in cancer survivors: an individual participant data meta-analysis.Journal of cancer survivorship : research and practice · 2024Pooled it
- 6th and 7th International consensus guidelines for the management of advanced breast cancer (ABC guidelines 6 and 7).Breast (Edinburgh, Scotland) · 2024Guideline
- Recruitment rates and strategies in exercise trials in cancer survivorship: a systematic review.Journal of cancer survivorship : research and practice · 2024Pooled it
- Is poor sleep quality associated with poor neurocognitive outcome in cancer survivors? A systematic review.Journal of cancer survivorship : research and practice · 2024Pooled it
- Prevalence and assessment tools of cancer-related cognitive impairment in lung cancer survivors: a systematic review and proportional meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Pooled it
- Chemotherapy-induced cognitive impairment in breast cancer survivors: A systematic review of studies from 2000 to 2021.Cancer reports (Hoboken, N.J.) · 2024Pooled it
- Interventions promoting cognitive function in patients experiencing cancer related cognitive impairment: A systematic review.Psycho-oncology · 2023Pooled it
- Effective non-pharmacological interventions for cancer related cognitive impairment in adults (excluding central nervous system or head and neck cancer): systematic review and meta-analysis.European journal of physical and rehabilitation medicine · 2022Pooled it
- A Systematic Review of the Impact of Physical Exercise-Induced Increased Resting Cerebral Blood Flow on Cognitive Functions.Frontiers in aging neuroscience · 2022Pooled it
- Interventions for multidimensional aspects of breast cancer-related fatigue: a meta-analytic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Pooled it
- Effects of Yoga-Based Interventions on Cancer-Associated Cognitive Decline: a Systematic Review.Current oncology reports · 2020Pooled it
- The Effect of Exercise on Cancer-Related Cognitive Impairment and Applications for Physical Therapy: Systematic Review of Randomized Controlled Trials.Physical therapy · 2020Pooled it
- The relationship between diet and cognitive function in adult cancer survivors: a systematic review.Journal of cancer survivorship : research and practice · 2019Pooled it
- The effects of exercise referral schemes in the United Kingdom in those with cardiovascular, mental health, and musculoskeletal disorders: a preliminary systematic review.BMC public health · 2018Pooled it
- Physical activity for women with breast cancer after adjuvant therapy.The Cochrane database of systematic reviews · 2018Pooled it
- A Systematic Review of Exercise Systematic Reviews in the Cancer Literature (2005-2017).PM & R : the journal of injury, function, and rehabilitation · 2017Pooled it
- Factors associated with perceived cognitive impairment in patients with advanced lung cancer: a cross-sectional analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Trial
- Cognitive Functioning and Health in Hispanic/Latina Breast Cancer Survivors.Journal of immigrant and minority health · 2022Trial
16 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This systematic review analyzes current data on effects of exercise interventions and physical activity behavior on objective and subjective cancer related cognitive impairments (CRCI). Out of the 19 studies which met all inclusion criteria, five RCTs investigated rodents, whereas the other 14 trials explored humans and these included six RCTs, one controlled trial, two prospective noncontrolled trials, one case series, one observational study, and three cross-sectional studies. The results from animal models revealed positive effects of exercise during and after chemotherapy or radiation on structural alterations of the central nervous system, physiological as well as neuropsychological outcomes. The overall study quality in patient studies was poor. The current data on intervention studies showed preliminary positive effects of Asian-influenced movement programs (e.g., Yoga) with benefits on self-perceived cognitive functions as well as a reduction of chronic inflammation for breast cancer patients in the aftercare. Exercise potentially contributes to the prevention and rehabilitation of CRCI. Additional RCTs with standardized neuropsychological assessments and controlling for potential confounders are needed to confirm and expand preliminary findings.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.