ReviewJournal of asthma and allergy2016
Sleep-disordered breathing in children with asthma: a systematic review on the impact of treatment.
Review in Journal of asthma and allergy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 87 citations in OpenAlex.
- Prevalence and Risk Factors of Sleep Disordered Breathing in School-Aged Children with Bronchopulmonary Dysplasia.Pediatric allergy, immunology, and pulmonology · 2026Article
- Overnight deep inspiration patterns in obstructive sleep apnea patients with and without asthma.Physiological reports · 2025Article
- Childhood Asthma Biomarkers Derived from Plasma and Saliva Exosomal miRNAs.International journal of molecular sciences · 2025Article
- Risk and Protective Factors for Obstructive Sleep Apnea Syndrome Throughout Lifespan: From Pregnancy to Adolescence.Children (Basel, Switzerland) · 2025Review
- Article
- Obstructive Sleep Apnea Is Associated with Worsened Hospital Outcomes in Children Hospitalized with Asthma.Children (Basel, Switzerland) · 2024Article
- Asthma and Sleep-disordered Breathing Overlap in School-aged Children.Annals of the American Thoracic Society · 2024Article
- Pediatric asthma comorbidities: Global impact and unmet needs.The World Allergy Organization journal · 2024Review
- Positive Airway Pressure Device Care and Cleaning Practices in the Pediatric Home.Respiratory care · 2023Article
- Unplanned Postoperative Reintubation in Children with Bronchial Asthma.Journal of pediatric intensive care · 2022Article
- Associations between sleep, obesity, and asthma in urban minority children.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022Article
- The Association between Asthma and OSA in Children.Children (Basel, Switzerland) · 2022Article
- Paediatric asthma and non-allergic comorbidities: A review of current risk and proposed mechanisms.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2022Review
- Sleep disorders in children with asthma.Pediatric pulmonology · 2022Review
- Orthodontic interventions as a management option for children with residual obstructive sleep apnea: a cohort study protocol.BMJ open · 2022Article
- The Role of Comorbidities in Difficult-to-Control Asthma in Adults and Children.The journal of allergy and clinical immunology. In practice · 2022Article
- Association of Parasomnia Symptoms with Risk of Childhood Asthma and the Role of Preterm Birth.Nature and science of sleep · 2022Article
- Clinical and functional characteristics of OSA in children with comorbid asthma treated by leukotriene receptor antagonist: A descriptive study.Frontiers in neurology · 2022Article
- Association of Symptoms of Sleep-Related Breathing Disorders with Asthma Control in Indian Children.Indian journal of pediatrics · 2022Article
- Do not forget asthma comorbidities in pediatric severe asthma!Frontiers in pediatrics · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe objective was to perform a systematic review in order to describe the relationship between asthma and sleep-disordered breathing (SDB) in children, especially regarding the impact of treatment and management.
methodsWe performed an electronic search in MEDLINE, EMBASE, and LILACS database. Study inclusion criteria were the following: 1) studies that examined the relationship between asthma/wheezing and SDB/obstructive sleep apnea (OSA); and 2) studies conducted in children <18 years of age. Primary outcomes were the prevalence of asthma and SDB, the tests used for diagnosis, and the influence of their treatment and management.
resultsOne thousand and twenty studies were identified, among which 32 were selected (n=143,343 children; 51% males; age [mean ± standard deviation] 8.4±2.5 years). Most studies (n=26) diagnosed SDB using questionnaires or clinical history. Nine studies performed a sleep study for diagnosing OSA. The diagnosis of asthma was based on clinical history (n=16), previous medical diagnosis (n=4), questionnaires (n=12), and spirometry (n=5). Children with asthma were more likely to develop habitual snoring and OSA, and children with SDB were more likely to develop asthma. Moreover, asthma was associated with more severe OSA, and the presence of SDB was associated with severe asthma. Treatment of SDB with adenotonsillectomy was associated with significant asthma improvement.
conclusionThe relationship between asthma and SDB appears to be bidirectional, and adenotonsillectomy appears to improve asthma control. Future trials on how asthma treatment could impact on SDB are needed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.